| Literature DB >> 17604170 |
Victor R Guarino1, Veranja Karunaratne, Valentino J Stella.
Abstract
The objective of this report is to introduce the novel concept of utilizing sulfenamides as prodrugs for compounds containing an NH-acidic functionality, particularly weakly acidic amide-type functionalities (amides, ureas, carbamates, etc.). Included are the syntheses and physicochemical characterizations of some model sulfenamides to illustrate the promise of this new prodrug technology.Entities:
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Year: 2007 PMID： 17604170 DOI： 10.1016/j.bmcl.2007.06.037
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823