Literature DB >> 17603196

Medicinal flowers. XVI. New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng.

Masayuki Yoshikawa1, Sachiko Sugimoto, Seikou Nakamura, Hayaka Sakumae, Hisashi Matsuda.   

Abstract

The oligoglycoside fraction from the flower buds of Panax ginseng C. A. MEYER (Araliaceae) was found to show protective effects on ethanol-induced gastric mucosal lesions in rats. From the oligoglycoside fraction, new dammarane-type triterpene tetraglycosides, floralginsenosides M, N, O, and P, were isolated together with the major oligoglycosides ginsenoside Rd and Re. The structures of the new floralginsenosides were elucidated on the basis of chemical and physicochemical evidence. Ginsenoside Rd (protopanaxadiol 3,20-O-bisdesmoside) exhibited inhibitory effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats.

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Year:  2007        PMID： 17603196     DOI： 10.1248/cpb.55.1034

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  9 in total

Review 1.  Isolation and analysis of ginseng: advances and challenges.

Authors:  Lian-Wen Qi; Chong-Zhi Wang; Chun-Su Yuan
Journal:  Nat Prod Rep       Date:  2011-01-24       Impact factor: 13.423

Review 2.  Insights into Recent Studies on Biotransformation and Pharmacological Activities of Ginsenoside Rd.

Authors:  Xiaoping Song; Lina Wang; Daidi Fan
Journal:  Biomolecules       Date:  2022-03-28

3.  Gastroprotective activity of isopulegol on experimentally induced gastric lesions in mice: investigation of possible mechanisms of action.

Authors:  Maria Izabel Gomes Silva; Brinell Arcanjo Moura; Manuel Rufino de Aquino Neto; Adriana da Rocha Tomé; Nayrton Flávio Moura Rocha; Alyne Mara Rodrigues de Carvalho; Danielle Silveira Macêdo; Silvânia Maria Mendes Vasconcelos; Damião Pergentino de Sousa; Glauce Socorro de Barros Viana; Francisca Cléa Florenço de Sousa
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2009-05-29       Impact factor: 3.000

Review 4.  Chemical diversity of ginseng saponins from Panax ginseng.

Authors:  Byong-Kyu Shin; Sung Won Kwon; Jeong Hill Park
Journal:  J Ginseng Res       Date:  2015-01-10       Impact factor: 6.060

5.  Rapid characterization of ginsenosides in the roots and rhizomes of Panax ginseng by UPLC-DAD-QTOF-MS/MS and simultaneous determination of 19 ginsenosides by HPLC-ESI-MS.

Authors:  Hong-Ping Wang; You-Bo Zhang; Xiu-Wei Yang; Da-Qing Zhao; Ying-Ping Wang
Journal:  J Ginseng Res       Date:  2015-12-17       Impact factor: 6.060

6.  Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng.

Authors:  Dong-Hyun Kim
Journal:  J Ginseng Res       Date:  2012-01       Impact factor: 6.060

7.  Dammarane-type triterpene saponins from the flowers of Panax notoginseng.

Authors:  Jing-Rong Wang; Yuko Yamasaki; Takashi Tanaka; Isao Kouno; Zhi-Hong Jiang
Journal:  Molecules       Date:  2009-06-10       Impact factor: 4.411

8.  A Strategy for Simultaneous Isolation of Less Polar Ginsenosides, Including a Pair of New 20-Methoxyl Isomers, from Flower Buds of Panax ginseng.

Authors:  Sha-Sha Li; Ke-Ke Li; Fei Xu; Li Tao; Li Yang; Shu-Xiao Chen; Xiao-Jie Gong
Journal:  Molecules       Date:  2017-03-10       Impact factor: 4.411

Review 9.  Advances in Saponin Diversity of Panax ginseng.

Authors:  Xiangmin Piao; Hao Zhang; Jong Pyo Kang; Dong Uk Yang; Yali Li; Shifeng Pang; Yinping Jin; Deok Chun Yang; Yingping Wang
Journal:  Molecules       Date:  2020-07-29       Impact factor: 4.411
  9 in total

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