Literature DB >> 17602308

Testicular microlithiasis: prevalence and risk of concurrent and interval development of testicular tumor in a referred population.

Imran Ahmad1, Nalagatla Sarath Krishna, Ross Clark, Robert Nairn, Naels Al-Saffar.   

Abstract

AIMS: To identify prevalence of testicular microlithiasis on ultrasound in a referred population and risk of concurrent and interval testicular tumor development.
METHODS: Retrospective review of our radiology database revealed 4363 scrotal ultrasounds were performed over a six-year period. Ultrasound findings were correlated with our hospital pathological database. The association of intratesticular microlithiasis and confirmed testicular cancers were assessed by means of a Fisher exact test.
RESULTS: Testicular microlithiasis was identified in 32 of the 4259 patients (0.75% of screened population). In the same time period 83 testicular tumors were identified on initial scanning (2.00% of screened population). Three patients with tumor had coexisting microlithiasis (9.4% incidence), whilst a further two had interval development of tumor. The follow-up of the microlithiasis patients ranged from 3 to 72 months (mean 33.9 months, median 40 months).
CONCLUSIONS: Interval development of testicular tumor is a documented phenomenon. As the incidence in detection of microlithiasis increases secondary to advances in ultrasound technology, follow-up becomes financially prohibitive. We advocate regular self-examination as the primary follow-up of otherwise well patients with testicular microlithiasis.

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Year:  2007        PMID: 17602308     DOI: 10.1007/s11255-007-9203-0

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  29 in total

1.  Testicular microlithiasis: prevalence and tumor risk in a population referred for scrotal sonography.

Authors:  J E Cast; W M Nelson; A S Early; S Biyani; G Cooksey; N G Warnock; D J Breen
Journal:  AJR Am J Roentgenol       Date:  2000-12       Impact factor: 3.959

2.  Testicular microlithiasis and subsequent development of metastatic germ cell tumor.

Authors:  D P Frush; M A Kliewer; J F Madden
Journal:  AJR Am J Roentgenol       Date:  1996-10       Impact factor: 3.959

3.  Testicular microlithiasis: US follow-up.

Authors:  H F Bennett; W D Middleton; A D Bullock; S A Teefey
Journal:  Radiology       Date:  2001-02       Impact factor: 11.105

4.  Yolk sac tumor of the testis discovered on a routine annual sonogram in a boy with testicular microlithiasis.

Authors:  N McEniff; F Doherty; J Katz; C A Schrager; G Klauber
Journal:  AJR Am J Roentgenol       Date:  1995-04       Impact factor: 3.959

5.  Testicular microlithiasis: sonographic and clinical features.

Authors:  D L Janzen; J R Mathieson; J I Marsh; P L Cooperberg; P del Rio; R H Golding; M D Rifkin
Journal:  AJR Am J Roentgenol       Date:  1992-05       Impact factor: 3.959

6.  Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men.

Authors:  C A de Gouveia Brazao; F H Pierik; J W Oosterhuis; G R Dohle; L H J Looijenga; R F A Weber
Journal:  J Urol       Date:  2004-01       Impact factor: 7.450

7.  Testicular microlithiasis: imaging appearances and pathologic correlation.

Authors:  M L Backus; L A Mack; W D Middleton; B F King; T C Winter; L D True
Journal:  Radiology       Date:  1994-09       Impact factor: 11.105

Review 8.  Testicular microlithiasis: a case report and review of the literature.

Authors:  Nathan Lawrentschuk; Stephen J S Brough; Rex J de Ryke
Journal:  ANZ J Surg       Date:  2003-05       Impact factor: 1.872

Review 9.  Testicular microlithiasis: a review and its association with testicular cancer.

Authors:  Hani H Rashid; Louis R Cos; Eric Weinberg; Edward M Messing
Journal:  Urol Oncol       Date:  2004 Jul-Aug       Impact factor: 3.498

10.  Testicular calcifications: incidence, histology and proposed pathological criteria for testicular microlithiasis.

Authors:  A A Renshaw
Journal:  J Urol       Date:  1998-11       Impact factor: 7.450

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  2 in total

1.  Testicular microlithiasis: is there a need for surveillance in the absence of other risk factors?

Authors:  Jonathan Richenberg; Nick Brejt
Journal:  Eur Radiol       Date:  2012-06-19       Impact factor: 5.315

2.  Testicular microlithiasis and testicular tumor: a review of the literature.

Authors:  Louis Leblanc; François Lagrange; Pierre Lecoanet; Baptiste Marçon; Pascal Eschwege; Jacques Hubert
Journal:  Basic Clin Androl       Date:  2018-07-09
  2 in total

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