| Literature DB >> 17601734 |
Philip Wickens1, Chengzhi Zhang, Xin Ma, Qian Zhao, John Amatruda, William Bullock, Michael Burns, Louis-David Cantin, Chih-Yuan Chuang, Thomas Claus, Miao Dai, Fernando Dela Cruz, David Dickson, Frederick J Ehrgott, Dongping Fan, Sarah Heald, Martin Hentemann, Christiana I Iwuagwu, Jeffrey S Johnson, Ellalahewage Kumarasinghe, David Ladner, Rico Lavoie, Sidney Liang, James N Livingston, Derek Lowe, Steve Magnuson, Gretchen Mannelly, Ingo Mugge, Herbert Ogutu, Susan Pleasic-Williams, Robert W Schoenleber, Jeff Shapiro, Tatiana Shelekhin, Laurel Sweet, Christopher Town, Manami Tsutsumi.
Abstract
A series of indane acetic acid derivatives were prepared which show a spectrum of activity as insulin sensitizers and PPAR-alpha and PPAR-delta ligands. In vivo data are presented for insulin sensitizers with selectivity for PPAR-delta over PPAR-alpha.Entities:
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Year: 2007 PMID： 17601734 DOI： 10.1016/j.bmcl.2007.03.057
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823