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Literature DB >> 17601631

Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation.

Ryotaro Morinaga¹, Isamu Okamoto, Kazuyuki Furuta, Yukiko Kawano, Masaru Sekijima, Kensaku Dote, Takao Satou, Kazuto Nishio, Masahiro Fukuoka, Kazuhiko Nakagawa.

Abstract

We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC.

Entities: Disease Gene

Mesh：

Substances：
ErbB Receptors

Year: 2007 PMID： 17601631 DOI： 10.1016/j.lungcan.2007.05.014

Source DB: PubMed Journal: Lung Cancer ISSN： 0169-5002 Impact factor: 5.705

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Cited

53 in total

1. Molecular and Histological Changes in Post-Treatment Biopsies of Non-Squamous Non-Small Cell Lung Cancer: A Retrospective Study.

Authors: S Vatrano; L Righi; T Vavalá; I Rapa; M Busso; S Izzo; S Cappia; A Veltri; M Papotti; G V Scagliotti; S Novello
Journal: Target Oncol Date: 2016-04 Impact factor: 4.493

Review 2. Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin.

Authors: Matthew G Oser; Matthew J Niederst; Lecia V Sequist; Jeffrey A Engelman
Journal: Lancet Oncol Date: 2015-04 Impact factor: 41.316

Review 3. Biopsy and re-biopsy in lung cancer: the oncologist requests and the role of endobronchial ultrasounds transbronchial needle aspiration.

Authors: Alessandro Tuzi; Elena Bolzacchini; Matteo B Suter; Alice Giaquinto; Antonio Passaro; Stefania Gobba; Ilaria Vallini; Graziella Pinotti
Journal: J Thorac Dis Date: 2017-05 Impact factor: 2.895

4. Contrast-enhanced computerized tomography combined with a targeted nanoparticle contrast agent for screening for early-phase non-small cell lung cancer.

Authors: Ninglu Yuan; Xiaohe Zhang; Yonghui Cao; Xiaojie Jiang; Si Zhao; Yingying Feng; Yimeng Fan; Zhitao Lu; Hongmei Gao
Journal: Exp Ther Med Date: 2017-09-19 Impact factor: 2.447

Review 5. New Approaches to SCLC Therapy: From the Laboratory to the Clinic.

Authors: John T Poirier; Julie George; Taofeek K Owonikoko; Anton Berns; Elisabeth Brambilla; Lauren A Byers; David Carbone; Huanhuan J Chen; Camilla L Christensen; Caroline Dive; Anna F Farago; Ramaswamy Govindan; Christine Hann; Matthew D Hellmann; Leora Horn; Jane E Johnson; Young S Ju; Sumin Kang; Mark Krasnow; James Lee; Se-Hoon Lee; Jonathan Lehman; Benjamin Lok; Christine Lovly; David MacPherson; David McFadden; John Minna; Matthew Oser; Keunchil Park; Kwon-Sik Park; Yves Pommier; Vito Quaranta; Neal Ready; Julien Sage; Giorgio Scagliotti; Martin L Sos; Kate D Sutherland; William D Travis; Christopher R Vakoc; Sarah J Wait; Ignacio Wistuba; Kwok Kin Wong; Hua Zhang; Jillian Daigneault; Jacinta Wiens; Charles M Rudin; Trudy G Oliver
Journal: J Thorac Oncol Date: 2020-02-01 Impact factor: 15.609

6. Small cell lung cancer transformation and the T790M mutation: A case report of two acquired mechanisms of TKI resistance detected in a tumor rebiopsy and plasma sample of EGFR-mutant lung adenocarcinoma.

Authors: Greta Alì; Rossella Bruno; Mirella Giordano; Irene Prediletto; Letizia Marconi; Simonetta Zupo; Franco Fedeli; Alessandro Ribechini; Antonio Chella; Gabriella Fontanini
Journal: Oncol Lett Date: 2016-09-26 Impact factor: 2.967

Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation.

1. Molecular and Histological Changes in Post-Treatment Biopsies of Non-Squamous Non-Small Cell Lung Cancer: A Retrospective Study.

Review 2. Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin.

Review 3. Biopsy and re-biopsy in lung cancer: the oncologist requests and the role of endobronchial ultrasounds transbronchial needle aspiration.

4. Contrast-enhanced computerized tomography combined with a targeted nanoparticle contrast agent for screening for early-phase non-small cell lung cancer.

Review 5. New Approaches to SCLC Therapy: From the Laboratory to the Clinic.

6. Small cell lung cancer transformation and the T790M mutation: A case report of two acquired mechanisms of TKI resistance detected in a tumor rebiopsy and plasma sample of EGFR-mutant lung adenocarcinoma.

Review 7. EGFR-TKI resistance in NSCLC patients: mechanisms and strategies.

Review 8. Histological transformation after acquired resistance to epidermal growth factor tyrosine kinase inhibitors.

Review 9. Histopathological transformation to small-cell lung carcinoma in non-small cell lung carcinoma tumors.

Review 10. Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer.