OBJECTIVE: To examine the influence of nonthermal ultrasound on mechano-growth factor (MGF) messenger ribonucleic acid (mRNA) expression after blunt trauma. DESIGN: A 2x4 factorial multivariate analysis of variance design. SETTING: University research laboratory. ANIMALS: Thirty-six 3- to 4-month-old male Wistar rats (mean weight, 280.8+/-21.5g). Thirty-two received a bilateral contusion injury to the gastrocnemius via a drop mass technique. Four were control animals. INTERVENTION: Ultrasound treatment (frequency, 3MHz; intensity, 0.3W/cm(2); continuous duty cycle) was started 24 hours postinjury and delivered for 5 minutes daily on 4 consecutive days. Treatment was on the left hindlimb and the contralateral right hindlimb was the nonultrasound control. MAIN OUTCOME MEASURES: Muscle mass (in grams) and MGF mRNA expression as measured via real-time reverse transcriptase polymerase chain reaction. RESULTS: Ultrasound had no effect on muscle mass (F(1,28)=2.723, P=.110, 1-beta=.357, eta(2)=.089). Ultrasound treatments decreased MGF mRNA expression in the treated limb compared with the nontreated hindlimb (F(1,28)=6.605, P=.016, 1-beta=.699, eta(2)=.191). CONCLUSIONS: The nonthermal ultrasound treatments resulted in decreased MGF mRNA expression after blunt trauma to the gastrocnemius muscles.
OBJECTIVE: To examine the influence of nonthermal ultrasound on mechano-growth factor (MGF) messenger ribonucleic acid (mRNA) expression after blunt trauma. DESIGN: A 2x4 factorial multivariate analysis of variance design. SETTING: University research laboratory. ANIMALS: Thirty-six 3- to 4-month-old male Wistar rats (mean weight, 280.8+/-21.5g). Thirty-two received a bilateral contusion injury to the gastrocnemius via a drop mass technique. Four were control animals. INTERVENTION: Ultrasound treatment (frequency, 3MHz; intensity, 0.3W/cm(2); continuous duty cycle) was started 24 hours postinjury and delivered for 5 minutes daily on 4 consecutive days. Treatment was on the left hindlimb and the contralateral right hindlimb was the nonultrasound control. MAIN OUTCOME MEASURES: Muscle mass (in grams) and MGF mRNA expression as measured via real-time reverse transcriptase polymerase chain reaction. RESULTS: Ultrasound had no effect on muscle mass (F(1,28)=2.723, P=.110, 1-beta=.357, eta(2)=.089). Ultrasound treatments decreased MGF mRNA expression in the treated limb compared with the nontreated hindlimb (F(1,28)=6.605, P=.016, 1-beta=.699, eta(2)=.191). CONCLUSIONS: The nonthermal ultrasound treatments resulted in decreased MGF mRNA expression after blunt trauma to the gastrocnemius muscles.
Authors: Nicole M McBrier; Thomas Neuberger; Craig R Denegar; Neil A Sharkey; Andrew G Webb Journal: J Am Assoc Lab Anim Sci Date: 2009-03 Impact factor: 1.232
Authors: Gian Nicola Bisciotti; Piero Volpi; Maurizio Amato; Giampietro Alberti; Francesco Allegra; Alessandro Aprato; Matteo Artina; Alessio Auci; Corrado Bait; Gian Matteo Bastieri; Luca Balzarini; Andrea Belli; Gianandrea Bellini; Pierfrancesco Bettinsoli; Alessandro Bisciotti; Andrea Bisciotti; Stefano Bona; Lorenzo Brambilla; Marco Bresciani; Michele Buffoli; Filippo Calanna; Gian Luigi Canata; Davide Cardinali; Giulia Carimati; Gabriella Cassaghi; Enrico Cautero; Emanuele Cena; Barbara Corradini; Alessandro Corsini; Cristina D'Agostino; Massimo De Donato; Giacomo Delle Rose; Francesco Di Marzo; Francesco Di Pietto; Drapchind Enrica; Cristiano Eirale; Luigi Febbrari; Paolo Ferrua; Andrea Foglia; Alberto Galbiati; Alberto Gheza; Carlo Giammattei; Francesco Masia; Gianluca Melegati; Biagio Moretti; Lorenzo Moretti; Roberto Niccolai; Antonio Orgiani; Claudio Orizio; Andrea Pantalone; Federica Parra; Paolo Patroni; Maria Teresa Pereira Ruiz; Marzio Perri; Stefano Petrillo; Luca Pulici; Alessandro Quaglia; Luca Ricciotti; Francesco Rosa; Nicola Sasso; Claudio Sprenger; Chiara Tarantola; Fabio Gianpaolo Tenconi; Fabio Tosi; Michele Trainini; Agostino Tucciarone; Ali Yekdah; Zarko Vuckovic; Raul Zini; Karim Chamari Journal: BMJ Open Sport Exerc Med Date: 2018-05-24