Literature DB >> 1760119

Silver sulphadiazine-induced haemolytic anaemia in a glucose-6-phosphate dehydrogenase-deficient burn patient.

A Eldad1, A Neuman, A Weinberg, P Benmeir, M Rotem, M R Wexler.   

Abstract

A 20-year-old soldier sustained 35 per cent body surface area burns by open flames. He was treated with topical application of 1 per cent silver sulphadiazine (SSD) twice daily. Four days postburn he developed acute haemolytic anaemia. Withdrawal of SSD was followed by complete recovery. A glucose-6-phosphate dehydrogenase (G6PD) deficiency was proven by pathological Motulski tests. Although the hazards of SSD are well indicated by the manufacturers, there appear to be no written reports of haemolysis induced by this drug in G6PD-deficient patients.

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Year:  1991        PMID： 1760119     DOI： 10.1016/s0305-4179(05)80083-x

Source DB:  PubMed          Journal:  Burns        ISSN： 0305-4179            Impact factor:   2.744


  5 in total

1.  The local treatment of burns with antibiotics.

Authors:  B Napoli; N D'Arpa; A Masellis; M Masellis
Journal:  Ann Burns Fire Disasters       Date:  2005-09-30

Review 2.  Use of silver in the prevention and treatment of infections: silver review.

Authors:  Amani D Politano; Kristin T Campbell; Laura H Rosenberger; Robert G Sawyer
Journal:  Surg Infect (Larchmt)       Date:  2013-02-28       Impact factor: 2.150

3.  Internally coated endotracheal tubes with silver sulfadiazine in polyurethane to prevent bacterial colonization: a clinical trial.

Authors:  Lorenzo Berra; Theodor Kolobow; Patrice Laquerriere; Betsey Pitts; Simone Bramati; Joshua Pohlmann; Chiara Marelli; Miriam Panzeri; Pietro Brambillasca; Federico Villa; Andrea Baccarelli; Sylvie Bouthors; Henry T Stelfox; Luca M Bigatello; Joel Moss; Antonio Pesenti
Journal:  Intensive Care Med       Date:  2008-04-17       Impact factor: 17.440

Review 4.  Medications and glucose-6-phosphate dehydrogenase deficiency: an evidence-based review.

Authors:  Ilan Youngster; Lidia Arcavi; Renata Schechmaster; Yulia Akayzen; Hen Popliski; Janna Shimonov; Svetlana Beig; Matitiahu Berkovitch
Journal:  Drug Saf       Date:  2010-09-01       Impact factor: 5.228

Review 5.  G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications.

Authors:  Lucio Luzzatto; Elisa Seneca
Journal:  Br J Haematol       Date:  2013-12-28       Impact factor: 6.998
  5 in total

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