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Literature DB >> 17600292

Pulmonary coagulopathy: a potential therapeutic target in different forms of lung injury.

Marcus J Schultz, Marcel Levi.

Abstract

Entities: Disease

Mesh：

Year: 2007 PMID： 17600292 PMCID： PMC2117247 DOI： 10.1136/thx.2006.067256

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

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29 in total

1. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome.

Authors: A Günther; P Mosavi; S Heinemann; C Ruppert; H Muth; P Markart; F Grimminger; D Walmrath; B Temmesfeld-Wollbrück; W Seeger
Journal: Am J Respir Crit Care Med Date: 2000-02 Impact factor: 21.405

2. Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury.

Authors: John A Belperio; Michael P Keane; Marie D Burdick; Vedang Londhe; Ying Ying Xue; Kewang Li; Roderick J Phillips; Robert M Strieter
Journal: J Clin Invest Date: 2002-12 Impact factor: 14.808

3. Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin.

Authors: William A Altemeier; Gustavo Matute-Bello; Charles W Frevert; Yasunobu Kawata; Osamu Kajikawa; Thomas R Martin; Robb W Glenny
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2004-05-14 Impact factor: 5.464

4. Efficacy and safety of recombinant human activated protein C for severe sepsis.

Authors: G R Bernard; J L Vincent; P F Laterre; S P LaRosa; J F Dhainaut; A Lopez-Rodriguez; J S Steingrub; G E Garber; J D Helterbrand; E W Ely; C J Fisher
Journal: N Engl J Med Date: 2001-03-08 Impact factor: 91.245

Review 5. Endothelium and disordered fibrin turnover in the injured lung: newly recognized pathways.

Authors: Steven Idell
Journal: Crit Care Med Date: 2002-05 Impact factor: 7.598

6. Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide.

Authors: Debra L Miller; Karen Welty-Wolf; Martha Sue Carraway; Mirella Ezban; Andrew Ghio; Hagir Suliman; Claude A Piantadosi
Journal: Am J Respir Cell Mol Biol Date: 2002-06 Impact factor: 6.914

1. Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.

Authors: Gloria-Beatriz Machado; Albanita V de Oliveira; Alessandra M Saliba; Carolina D M de Lima; José H R Suassuna; Maria-Cristina Plotkowski
Journal: Respir Res Date: 2011-08-05

1 in total

Pulmonary coagulopathy: a potential therapeutic target in different forms of lung injury.

1. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome.

2. Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury.

3. Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin.

4. Efficacy and safety of recombinant human activated protein C for severe sepsis.

Review 5. Endothelium and disordered fibrin turnover in the injured lung: newly recognized pathways.

6. Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide.

7. The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor.

8. Activation of protein C pathway in the airways.

9. Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia.

10. Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep.

1. Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.