Literature DB >> 17599320

Persistence of nevirapine in breast milk after discontinuation of treatment.

Chantelle Bennetto-Hood1, Grace M Aldrovandi, Jennifer R King, Kyra Woodman, Negar Ashouri, Edward P Acosta.   

Abstract

The objective of this study was to serially quantitate the concentration of nevirapine in breast milk after discontinuation of treatment. Samples were collected from both breasts of a human immunodeficiency virus-infected patient for 3 weeks. Nevirapine was quantifiable for up to 17 days after discontinuation of therapy; total nevirapine concentrations remained above the 90% inhibitory concentration for 6 days, and no differences were observed between breasts.

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Year:  2007        PMID： 17599320     DOI： 10.1086/519427

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  4 in total

1.  Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity.

Authors:  Angela Wahl; Caroline Baker; Rae Ann Spagnuolo; Lisa W Stamper; Genevieve G Fouda; Sallie R Permar; Katie Hinde; Louise Kuhn; Lars Bode; Grace M Aldrovandi; J Victor Garcia
Journal:  J Virol       Date:  2015-08-19       Impact factor: 5.103

2.  HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission.

Authors:  Dara A Lehman; Michael H Chung; Grace C John-Stewart; Barbra A Richardson; James Kiarie; John Kinuthia; Julie Overbaugh
Journal:  AIDS       Date:  2008-07-31       Impact factor: 4.177

3.  Temporal and lateral dynamics of HIV shedding and elevated sodium in breast milk among HIV-positive mothers during the first 4 months of breast-feeding.

Authors:  Katherine Semrau; Mrinal Ghosh; Chipepo Kankasa; Moses Sinkala; Prisca Kasonde; Mwiya Mwiya; Donald M Thea; Louise Kuhn; Grace M Aldrovandi
Journal:  J Acquir Immune Defic Syndr       Date:  2008-03-01       Impact factor: 3.731

4.  Cell-free (RNA) and cell-associated (DNA) HIV-1 and postnatal transmission through breastfeeding.

Authors:  James Ndirangu; Johannes Viljoen; Ruth M Bland; Siva Danaviah; Claire Thorne; Philippe Van de Perre; Marie-Louise Newell
Journal:  PLoS One       Date:  2012-12-28       Impact factor: 3.240
  4 in total

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