Literature DB >> 17598060

Is violence at presentation by patients with first-episode psychosis associated with duration of untreated psychosis?

Sharon R Foley1, Stephen Browne, Mary Clarke, Anthony Kinsella, Conall Larkin, Eadbhard O'Callaghan.   

Abstract

INTRODUCTION: Violence in first episode psychosis poses significant challenges for mental health staff and patients' families. Violence has been shown to be related to psychopathology. Duration of untreated psychosis (DUP) has been shown to influence psychopathology at presentation in first-episode psychosis, but little is known about the direct relationship between violence at presentation and DUP. We therefore sought to examine the relationship between these two variables.
METHODS: Patients were all individuals aged between 16 and 65 years, with a DSM-III-R diagnosis of psychotic illness, taking part in a First Episode study. We used the Structured Clinical Interview (SCID-I), Positive and Negative Symptom Scale (PANSS), Beiser Scale and the Modified Overt Aggression Scale (MOAS) to evaluate diagnosis, psychopathology, DUP and violent behaviour respectively. Data for each case were retrospectively examined for violence, for the week prior to and week following first contact with psychiatric services, blind to diagnosis, DUP and psychopathology scores.
RESULTS: We assessed 157 patients. About 46 patients (29%) were violent. Violence rates did not differ across diagnostic groups, while DUP varied significantly across diagnostic groups (P = 0.001). Violence was not associated with DUP across all psychoses (P = 0.41). In the schizophrenia subgroup (n = 94), thirty individuals (32%) were violent. In a logistic regression, logDUP was not associated with violence (P = 0.11). Violence was predicted by involuntary admission status (P = 0.04) and global positive symptoms (P = 0.03). DUP was associated weakly with negative symptoms (P = 0.01) but not associated with positive or general psychopathology. Neither pre nor post-contact violence was associated (P = 0.79 and P = 0.09 respectively) with DUP. DISCUSSION: Contrary to a recent study, we did not find an association between violence at presentation and DUP. The relationships between violence, DUP and psychopathology are complex and may be compounded by potential difficulties inherent in the PANSS.
CONCLUSION: Programs to reduce DUP may not impact on rates of violence at presentation in First Episode Psychosis (FEP).

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Year:  2007        PMID: 17598060     DOI: 10.1007/s00127-007-0217-9

Source DB:  PubMed          Journal:  Soc Psychiatry Psychiatr Epidemiol        ISSN: 0933-7954            Impact factor:   4.328


  13 in total

Review 1.  Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis.

Authors:  Diana O Perkins; Hongbin Gu; Kalina Boteva; Jeffrey A Lieberman
Journal:  Am J Psychiatry       Date:  2005-10       Impact factor: 18.112

2.  Aggressive behavior against self and others among first-admission patients with schizophrenia.

Authors:  T Steinert; C Wiebe; R P Gebhardt
Journal:  Psychiatr Serv       Date:  1999-01       Impact factor: 3.084

3.  Course of violence in patients with schizophrenia: relationship to clinical symptoms.

Authors:  M Krakowski; P Czobor; J C Chou
Journal:  Schizophr Bull       Date:  1999       Impact factor: 9.306

4.  Incidence and clinical correlates of aggression and violence at presentation in patients with first episode psychosis.

Authors:  Sharon R Foley; Brendan D Kelly; Mary Clarke; Orfhlaith McTigue; Maurice Gervin; Moyyad Kamali; Conall Larkin; Eadbhard O'Callaghan; Stephen Browne
Journal:  Schizophr Res       Date:  2005-01-01       Impact factor: 4.939

5.  Aggression in Asian patients with first-episode psychosis.

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6.  Aggressive incidents in first-episode psychosis.

Authors:  J Milton; S Amin; S P Singh; G Harrison; P Jones; T Croudace; I Medley; J Brewin
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7.  Violence and psychiatric disorder in the community: evidence from the Epidemiologic Catchment Area surveys.

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Journal:  Hosp Community Psychiatry       Date:  1990-07

8.  A national study of violent behavior in persons with schizophrenia.

Authors:  Jeffrey W Swanson; Marvin S Swartz; Richard A Van Dorn; Eric B Elbogen; H Ryan Wagner; Robert A Rosenheck; T Scott Stroup; Joseph P McEvoy; Jeffrey A Lieberman
Journal:  Arch Gen Psychiatry       Date:  2006-05

9.  Establishing the onset of psychotic illness.

Authors:  M Beiser; D Erickson; J A Fleming; W G Iacono
Journal:  Am J Psychiatry       Date:  1993-09       Impact factor: 18.112

10.  Profiles of aggression among psychiatric patients. I. Nature and prevalence.

Authors:  S R Kay; F Wolkenfeld; L M Murrill
Journal:  J Nerv Ment Dis       Date:  1988-09       Impact factor: 2.254

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Review 3.  Rates of homicide during the first episode of psychosis and after treatment: a systematic review and meta-analysis.

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Review 4.  Evidence for a relationship between the duration of untreated psychosis and the proportion of psychotic homicides prior to treatment.

Authors:  Matthew Large; Olav Nielssen
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2007-10-24       Impact factor: 4.328

5.  Recent violence and legal involvement among young adults with early psychosis enrolled in Coordinated Specialty Care.

Authors:  Stephanie A Rolin; Leslie A Marino; Leah G Pope; Michael T Compton; Rufina J Lee; Barry Rosenfeld; Merrill Rotter; Ilana Nossel; Lisa Dixon
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6.  The Positive and Negative Experiences of Caregiving for Siblings of Young People with First Episode Psychosis.

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7.  Alcohol abuse as the strongest risk factor for violent offending in patients with paranoid schizophrenia.

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  7 in total

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