Literature DB >> 17595942

There is no scientific rationale for race-based research.

Eddie L Hoover1.   

Abstract

For centuries, the colonial governments used a combination of race and ethnic characteristics to subjugate and control people of color, and scientists of the day provided evidence of the "natural order of things" to support national policies of domination, segregation and control. There have been many examples of events in the past 70 years to suggest that achievements by ethnic peoples are not genetically determined and that race and ethnicity are merely terms to describe external features, language, culture, social mores and folklore. BiDil was the first drug in this country approved by the FDA for use in a single "race" after a clinical trial that enrolled only members of that race. Thus arose the question of the efficacy of doing race-based research in humans. In order for this kind of research to have any scientific basis, each individually defined or self-declared race would have to have a 100% pure gene pool, and the data show that the gene pool among whites, blacks and Hispanics in America is very heterogeneous. This makes for far greater similarities among U.S. citizens than any perceived differences, and genomic science has failed to support the concept of racial categories in medicine. Scientists involved with the first mapping of the human genome have noted that there is no basis in the genetic code for race. That being the case, there appears to be no justification for race-based research among human beings.

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Year:  2007        PMID: 17595942      PMCID: PMC2574368     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  5 in total

1.  Race in epidemiology.

Authors:  P D Stolley
Journal:  Int J Health Serv       Date:  1999       Impact factor: 1.663

Review 2.  How a drug becomes "ethnic": law, commerce, and the production of racial categories in medicine.

Authors:  Jonathan Kahn
Journal:  Yale J Health Policy Law Ethics       Date:  2004

Review 3.  Is research into ethnicity and health racist, unsound, or important science?

Authors:  R Bhopal
Journal:  BMJ       Date:  1997-06-14

4.  A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure.

Authors:  J N Cohn; G Johnson; S Ziesche; F Cobb; G Francis; F Tristani; R Smith; W B Dunkman; H Loeb; M Wong
Journal:  N Engl J Med       Date:  1991-08-01       Impact factor: 91.245

5.  Perceptions and misperceptions of skin color.

Authors:  S H Caldwell; R Popenoe
Journal:  Ann Intern Med       Date:  1995-04-15       Impact factor: 25.391

  5 in total
  4 in total

Review 1.  Disparities in the provision of medical care: an outcome in search of an explanation.

Authors:  Elizabeth A Klonoff
Journal:  J Behav Med       Date:  2009-01-06

Review 2.  Socioeconomic determinants of respiratory health in patients with cystic fibrosis: implications for treatment strategies.

Authors:  Gabriela R Oates; Michael S Schechter
Journal:  Expert Rev Respir Med       Date:  2022-06-23       Impact factor: 4.300

3.  The Association Between Neighborhood Social Vulnerability and COVID-19 Testing, Positivity, and Incidence in Alabama and Louisiana.

Authors:  Gabriela R Oates; Lucia D Juarez; Ronald Horswell; San Chu; Lucio Miele; Mona N Fouad; William A Curry; Daniel Fort; William B Hillegass; Denise M Danos
Journal:  J Community Health       Date:  2021-05-09

Review 4.  Left behind: The potential impact of CFTR modulators on racial and ethnic disparities in cystic fibrosis.

Authors:  Meghan E McGarry; Elizabeth R Gibb; Gabriela R Oates; Michael S Schechter
Journal:  Paediatr Respir Rev       Date:  2021-12-22       Impact factor: 5.526

  4 in total

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