BACKGROUND: Effective control and management of severe malaria cases depends on a clear understanding of the local epidemiological factors and specific clinical manifestations of the disease in the different endemic regions. OBJECTIVES: To determine the prevalence of severe malaria and epidemiological factors that affect the development of malaria anaemia. METHODS: A cross-sectional survey was carried out among children below 5 years of age, at the Adeoyo State Maternity Hospital, Ibadan, Nigeria. Questionnaires and case histories were taken from patients clinically diagnosed of malaria. Thus, 372 volunteers were recruited into the study from the 3131 paediatric cases that reported over the 10-week period to the out-patient department (OPD) of the hospital. 229 (61.6%) of the recruited volunteers presented with fever (>37.5 degrees C) at consultation. These had malaria parasite and PCV tests done. RESULTS: Clinical diagnosis was confirmed microscopically in 78% (290/372) for Plasmodium infection using thick film slides. Anaemia (PCV <28%) prevalence was 28.2%. Factors that contributed to the rapid progression of uncomplicated malaria to severe status included: age of the child, level of parasitaemia, careless response and attitude of parents or guardians to fever in the children; parents' preoccupation with their jobs or other healthy children and unwillingness to use available health facilities. CONCLUSION: The study underscores the need for community involved partnership for malaria control especially through health education for the home management of malaria, especially among those experiencing some form of inequity in access to healthcare.
BACKGROUND: Effective control and management of severe malaria cases depends on a clear understanding of the local epidemiological factors and specific clinical manifestations of the disease in the different endemic regions. OBJECTIVES: To determine the prevalence of severe malaria and epidemiological factors that affect the development of malaria anaemia. METHODS: A cross-sectional survey was carried out among children below 5 years of age, at the Adeoyo State Maternity Hospital, Ibadan, Nigeria. Questionnaires and case histories were taken from patients clinically diagnosed of malaria. Thus, 372 volunteers were recruited into the study from the 3131 paediatric cases that reported over the 10-week period to the out-patient department (OPD) of the hospital. 229 (61.6%) of the recruited volunteers presented with fever (>37.5 degrees C) at consultation. These had malaria parasite and PCV tests done. RESULTS: Clinical diagnosis was confirmed microscopically in 78% (290/372) for Plasmodium infection using thick film slides. Anaemia (PCV <28%) prevalence was 28.2%. Factors that contributed to the rapid progression of uncomplicated malaria to severe status included: age of the child, level of parasitaemia, careless response and attitude of parents or guardians to fever in the children; parents' preoccupation with their jobs or other healthy children and unwillingness to use available health facilities. CONCLUSION: The study underscores the need for community involved partnership for malaria control especially through health education for the home management of malaria, especially among those experiencing some form of inequity in access to healthcare.
Authors: A R Berendt; D J Ferguson; J Gardner; G Turner; A Rowe; C McCormick; D Roberts; A Craig; R Pinches; B C Elford Journal: Parasitology Date: 1994 Impact factor: 3.234
Authors: C Uthaipibull; B Aufiero; S E Syed; B Hansen; J A Guevara Patiño; E Angov; I T Ling; K Fegeding; W D Morgan; C Ockenhouse; B Birdsall; J Feeney; J A Lyon; A A Holder Journal: J Mol Biol Date: 2001-04-13 Impact factor: 5.469
Authors: Roseangela I Nwuba; Olugbemiro Sodeinde; Chiaka I Anumudu; Yusuf O Omosun; Alexander B Odaibo; Anthony A Holder; Mark Nwagwu Journal: Infect Immun Date: 2002-09 Impact factor: 3.441
Authors: Andria Mousa; Abdullah Al-Taiar; Nicholas M Anstey; Cyril Badaut; Bridget E Barber; Quique Bassat; Joseph D Challenger; Aubrey J Cunnington; Dibyadyuti Datta; Chris Drakeley; Azra C Ghani; Victor R Gordeuk; Matthew J Grigg; Pierre Hugo; Chandy C John; Alfredo Mayor; Florence Migot-Nabias; Robert O Opoka; Geoffrey Pasvol; Claire Rees; Hugh Reyburn; Eleanor M Riley; Binal N Shah; Antonio Sitoe; Colin J Sutherland; Philip E Thuma; Stefan A Unger; Firmine Viwami; Michael Walther; Christopher J M Whitty; Timothy William; Lucy C Okell Journal: PLoS Med Date: 2020-10-19 Impact factor: 11.069