Literature DB >> 17592714

Osteomyelitis and intraosteoblastic Staphylococcus aureus.

Lawrence X Webb1, William Wagner, David Carroll, Holly Tyler, Faith Coldren, Eileen Martin.   

Abstract

Chronic osteomyelitis is a disease process that is characterized not infrequently by periods of clinical quiescence interspersed by symptomatic episodes of varying duration and severity. These periods of clinical quiescence have been attributed to several possible factors, including effective host defenses that keep the process at bay as well as glycocalyceal sequestration of the implicated pathogen. Recent work has demonstrated a potential third explanation for this phenomenon, that is, intracellular incorporation of the pathogen within the host osteoblast. This is a report of a successful osteoblast cell culture demonstrating the facultative intraosteoblastic location of a human osteomyelitis Staphylococcus aureus isolate as well as its microscopic features.

Entities:  

Mesh:

Year:  2007        PMID: 17592714

Source DB:  PubMed          Journal:  J Surg Orthop Adv        ISSN: 1548-825X


  9 in total

1.  Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages.

Authors:  Sandrine Lemaire; Françoise Van Bambeke; Paul M Tulkens
Journal:  Antimicrob Agents Chemother       Date:  2009-06-29       Impact factor: 5.191

Review 2.  Infection.

Authors:  Theodore Miclau; Andrew H Schmidt; Joseph C Wenke; Lawrence X Webb; Janette M Harro; Ranjani Prabhakara; Mark E Shirtliff
Journal:  J Orthop Trauma       Date:  2010-09       Impact factor: 2.512

3.  Osteomyelitis of the long bones.

Authors:  Jason H Calhoun; M M Manring; Mark Shirtliff
Journal:  Semin Plast Surg       Date:  2009-05       Impact factor: 2.314

4.  Interaction of Staphylococcus aureus with osteoblasts (Review).

Authors:  Sifeng Shi; Xianlong Zhang
Journal:  Exp Ther Med       Date:  2011-12-20       Impact factor: 2.447

5.  Proinflammatory response of human osteoblastic cell lines and osteoblast-monocyte interaction upon infection with Brucella spp.

Authors:  M Victoria Delpino; Carlos A Fossati; Pablo C Baldi
Journal:  Infect Immun       Date:  2008-12-22       Impact factor: 3.441

6.  Closed trauma, Mycoplasma hominis osteomyelitis, and the elusive diagnosis of Good's syndrome.

Authors:  Amanda Noska; Rawad Nasr; David Neville Williams
Journal:  BMJ Case Rep       Date:  2012-11-27

Review 7.  Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".

Authors:  Elysia A Masters; Ryan P Trombetta; Karen L de Mesy Bentley; Brendan F Boyce; Ann Lindley Gill; Steven R Gill; Kohei Nishitani; Masahiro Ishikawa; Yugo Morita; Hiromu Ito; Sheila N Bello-Irizarry; Mark Ninomiya; James D Brodell; Charles C Lee; Stephanie P Hao; Irvin Oh; Chao Xie; Hani A Awad; John L Daiss; John R Owen; Stephen L Kates; Edward M Schwarz; Gowrishankar Muthukrishnan
Journal:  Bone Res       Date:  2019-07-15       Impact factor: 13.567

8.  Ultrasonically enhanced rifampin activity against internalized Staphylococcus aureus.

Authors:  Si-Feng Shi; Xian-Long Zhang; Chen Zhu; DE-Sheng Chen; Yong-Yuan Guo
Journal:  Exp Ther Med       Date:  2012-10-22       Impact factor: 2.447

9.  PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts.

Authors:  Jean-Philippe Rasigade; Sophie Trouillet-Assant; Tristan Ferry; Binh An Diep; Anaïs Sapin; Yannick Lhoste; Jérémy Ranfaing; Cédric Badiou; Yvonne Benito; Michèle Bes; Florence Couzon; Sylvestre Tigaud; Gérard Lina; Jérôme Etienne; François Vandenesch; Frédéric Laurent
Journal:  PLoS One       Date:  2013-05-14       Impact factor: 3.240

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.