Literature DB >> 17592555

Imbalance in seminal fluid MIF indicates male infertility.

Bayan Aljabari1, Aldo E Calogero, Anna Perdichizzi, Enzo Vicari, Raja Karaki, Tarek Lahloub, Rashed Zatari, Khaleel El-Abed, Ferdinando Nicoletti, Edmund J Miller, Valentin A Pavlov, Yousef Al-Abed.   

Abstract

Macrophage migration inhibitory factor (MIF) is a ubiquitous cytokine that functions in reproduction and plays an important role in sperm maturation and motility. Here we reveal a correlation between MIF levels in human seminal fluid and fertility status. We identify an abnormal biphasic profile of MIF in the seminal fluid of patients with impaired sperm parameters. Our findings may be of interest for the development of a diagnostic method for fertility status.

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Year:  2007        PMID： 17592555      PMCID： PMC1892758          DOI： 10.2119/2006–00114.Aljabari

Source DB:  PubMed          Journal:  Mol Med        ISSN： 1076-1551            Impact factor:   6.354


  15 in total

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Journal:  Prostate       Date:  2003-07-01       Impact factor: 4.104

2.  ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.

Authors:  Yousef Al-Abed; Darrin Dabideen; Bayan Aljabari; Aline Valster; Davorka Messmer; Mahendar Ochani; Mahira Tanovic; Kanta Ochani; Michael Bacher; Ferdinando Nicoletti; Christine Metz; Valentin A Pavlov; Edmund J Miller; Kevin J Tracey
Journal:  J Biol Chem       Date:  2005-08-22       Impact factor: 5.157

3.  The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.

Authors:  E Rosengren; R Bucala; P Aman; L Jacobsson; G Odh; C N Metz; H Rorsman
Journal:  Mol Med       Date:  1996-01       Impact factor: 6.354

4.  Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes.

Authors:  Ivana Cvetkovic; Yousef Al-Abed; Djordje Miljkovic; Danijela Maksimovic-Ivanic; Jesse Roth; Michael Bacher; Hui Y Lan; Ferdinando Nicoletti; Stanislava Stosic-Grujicic
Journal:  Endocrinology       Date:  2005-03-24       Impact factor: 4.736

5.  Macrophage migration inhibitory factor production by Leydig cells: evidence for a role in the regulation of testicular function.

Authors:  A Meinhardt; M Bacher; J R McFarlane; C N Metz; J Seitz; M P Hedger; D M de Kretser; R Bucala
Journal:  Endocrinology       Date:  1996-11       Impact factor: 4.736

6.  Macrophage migration inhibitory factor in the human endometrium: expression and localization during the menstrual cycle and early pregnancy.

Authors:  F Arcuri; C Ricci; F Ietta; M Cintorino; S A Tripodi; I Cetin; E Garzia; F Schatz; P Klemi; R Santopietro; L Paulesu
Journal:  Biol Reprod       Date:  2001-04       Impact factor: 4.285

7.  Expression of macrophage migration inhibitory factor transcript and protein by first-trimester human trophoblasts.

Authors:  F Arcuri; M Cintorino; R Vatti; A Carducci; S Liberatori; L Paulesu
Journal:  Biol Reprod       Date:  1999-06       Impact factor: 4.285

8.  Macrophage migration inhibitory factor in the human epididymis and semen.

Authors:  Gilles Frenette; Christine Légaré; Fabrice Saez; Robert Sullivan
Journal:  Mol Hum Reprod       Date:  2005-07-28       Impact factor: 4.025

9.  High concentrations of the macrophage migration inhibitory factor in human seminal plasma and prostatic tissues.

Authors:  G Frenette; R R Tremblay; J Y Dubé; C Lazure; M Lemay
Journal:  Arch Androl       Date:  1998 Nov-Dec

Review 10.  Macrophage migration inhibitory factor: a regulator of innate immunity.

Authors:  Thierry Calandra; Thierry Roger
Journal:  Nat Rev Immunol       Date:  2003-10       Impact factor: 53.106
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  4 in total

Review 1.  Peptides in seminal fluid and their role in infertility: a potential role for opiorphin inhibition of neutral endopeptidase activity as a clinically relevant modulator of sperm motility: a review.

Authors:  Jayme S Bosler; Kelvin P Davies; Genevieve S Neal-Perry
Journal:  Reprod Sci       Date:  2014-05-22       Impact factor: 3.060

2.  Semen variables and sperm membrane protein profile of Saanen bucks (Capra hircus) in dry and rainy seasons of the northeastern Brazil (3°S).

Authors:  M F van Tilburg; M G F Salles; M M Silva; R A Moreira; F B Moreno; A C O Monteiro-Moreira; J A M Martins; M J D Cândido; A A Araújo; A A A Moura
Journal:  Int J Biometeorol       Date:  2014-08-03       Impact factor: 3.787

Review 3.  Seminal Plasma Proteomic Biomarkers of Oxidative Stress.

Authors:  Rossella Cannarella; Andrea Crafa; Federica Barbagallo; Laura M Mongioì; Rosita A Condorelli; Antonio Aversa; Aldo E Calogero; Sandro La Vignera
Journal:  Int J Mol Sci       Date:  2020-11-30       Impact factor: 5.923

Review 4.  Varicocele-Mediated Male Infertility: From the Perspective of Testicular Immunity and Inflammation.

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Journal:  Front Immunol       Date:  2021-08-31       Impact factor: 7.561
  4 in total

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