PURPOSE: To report bilateral plasmacytoma of the ciliary body in a healthy patient. METHODS: Clinicopathologic report. RESULTS: A 55-year-old woman with iritis developed an iridociliary mass in the left eye. Systemic evaluation was normal. Fine-needle aspiration (FNAB) of the mass revealed atypical, binucleate plasmacytoid cells with positive leukocyte common antigen staining, suggestive of plasmacytoma. The tumor was treated with 4000 cGy by using custom-designed plaque radiotherapy. The tumor completely resolved. Two years later, a similar iridociliary mass was noted in the right eye, and FNAB confirmed plasmacytoma. Plaque radiotherapy of 4000 cGy was delivered. At the 3-year follow-up, there has been no local recurrence or evidence of systemic multiple myeloma or monoclonal gammopathy. CONCLUSIONS: Extramedullary plasmacytoma can involve the uvea and rarely manifest multiplicity. Long-term monitoring for systemic plasma cell dyscrasia is warranted.
PURPOSE: To report bilateral plasmacytoma of the ciliary body in a healthy patient. METHODS: Clinicopathologic report. RESULTS: A 55-year-old woman with iritis developed an iridociliary mass in the left eye. Systemic evaluation was normal. Fine-needle aspiration (FNAB) of the mass revealed atypical, binucleate plasmacytoid cells with positive leukocyte common antigen staining, suggestive of plasmacytoma. The tumor was treated with 4000 cGy by using custom-designed plaque radiotherapy. The tumor completely resolved. Two years later, a similar iridociliary mass was noted in the right eye, and FNAB confirmed plasmacytoma. Plaque radiotherapy of 4000 cGy was delivered. At the 3-year follow-up, there has been no local recurrence or evidence of systemic multiple myeloma or monoclonal gammopathy. CONCLUSIONS: Extramedullary plasmacytoma can involve the uvea and rarely manifest multiplicity. Long-term monitoring for systemic plasma cell dyscrasia is warranted.
Authors: Sarah E Coupland; Andrew Dodson; Hongxiang Liu; Ming-Qing Du; Martina Angi; Bertil E Damato Journal: Graefes Arch Clin Exp Ophthalmol Date: 2012-12-12 Impact factor: 3.117
Authors: Kafayat A Oyemade; Scott L Stafford; Morie A Gertz; Sanjay V Patel; Keith H Baratz; Lauren A Dalvin Journal: Am J Ophthalmol Case Rep Date: 2022-04-10