Literature DB >> 17590557

Standardization and stability studies of neuroprotective lipid soluble fraction obtained from Curcuma longa.

Vikas Jain1, Vure Prasad, R Pal, S Singh.   

Abstract

The lipid soluble fraction of curcuma longa, i.e. herbal medicament (HM) was isolated from rhizome of curcuma longa by solvent extraction method. The identification of chemical constituent present in HM was done with GC, GC-MS. The standardization of HM was done using HPLC method on the basis of three-marker compound isolated, i.e. ar-turmerone, turmerone and curlone. The effect of temperature, pH and light on stability of marker compounds of HM was studied. The composition of marker compound in HM was found to be 50-60%. The content of curcumnoids, another bioactive constituent present in HM was found to be 0.32-0.55%. The HM was found to be stable at different temperature and pH but light sensitive.

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Year:  2007        PMID: 17590557     DOI: 10.1016/j.jpba.2007.05.009

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  9 in total

1.  Anti-arthritic effects and toxicity of the essential oils of turmeric (Curcuma longa L.).

Authors:  Janet L Funk; Jennifer B Frye; Janice N Oyarzo; Huaping Zhang; Barbara N Timmermann
Journal:  J Agric Food Chem       Date:  2010-01-27       Impact factor: 5.279

2.  Curcuma oil: reduces early accumulation of oxidative product and is anti-apoptogenic in transient focal ischemia in rat brain.

Authors:  Priyanka Rathore; Preeti Dohare; Saurabh Varma; Aparajita Ray; Uma Sharma; N R Jagannathan; N R Jaganathanan; Madhur Ray
Journal:  Neurochem Res       Date:  2007-10-23       Impact factor: 3.996

3.  Curcuma oil ameliorates insulin resistance & associated thrombotic complications in hamster & rat.

Authors:  Vishal Singh; Manish Jain; Ankita Misra; Vivek Khanna; Prem Prakash; Richa Malasoni; Anil Kumar Dwivedi; Madhu Dikshit; Manoj Kumar Barthwal
Journal:  Indian J Med Res       Date:  2015-06       Impact factor: 2.375

4.  Redox properties of ginger extracts: Perspectives of use of Zingiber officinale Rosc. as antidiabetic agent.

Authors:  Lucia Račková; Máriá Cupáková; Anton Tažký; Júlia Mičová; Emil Kolek; Daniela Košt'álová
Journal:  Interdiscip Toxicol       Date:  2013-03

5.  Liposomal formulation of turmerone-rich hexane fractions from Curcuma longa enhances their antileishmanial activity.

Authors:  Ana Claudia F Amaral; Luciana A Gomes; Jefferson Rocha de A Silva; José Luiz P Ferreira; Aline de S Ramos; Maria do Socorro S Rosa; Alane B Vermelho; Igor A Rodrigues
Journal:  Biomed Res Int       Date:  2014-06-18       Impact factor: 3.411

6.  Neuroprotective efficacy and therapeutic window of curcuma oil: in rat embolic stroke model.

Authors:  Preeti Dohare; Puja Garg; Uma Sharma; N R Jagannathan; Madhur Ray
Journal:  BMC Complement Altern Med       Date:  2008-09-30       Impact factor: 3.659

7.  Enhanced inhibitory effect of curcumin via reactive oxygen species generation in human nasopharyngeal carcinoma cells following purple-light irradiation.

Authors:  Dujuan Wang; Jiang Hu; Lin Lv; Xiuwen Xia; Jianzhong Liu; Xiaoyuan Li
Journal:  Oncol Lett       Date:  2013-05-08       Impact factor: 2.967

8.  A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity.

Authors:  Minakshi Rana; Preeti Maurya; Sukka S Reddy; Vishal Singh; Hafsa Ahmad; Anil K Dwivedi; Madhu Dikshit; Manoj K Barthwal
Journal:  Front Pharmacol       Date:  2016-07-25       Impact factor: 5.810

Review 9.  Non-Curcuminoids from Turmeric and Their Potential in Cancer Therapy and Anticancer Drug Delivery Formulations.

Authors:  Akhila Nair; Augustine Amalraj; Joby Jacob; Ajaikumar B Kunnumakkara; Sreeraj Gopi
Journal:  Biomolecules       Date:  2019-01-02
  9 in total

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