Literature DB >> 17589258

Scar lymphedema: fact or fiction?

Anne G Warren1, Sumner A Slavin.   

Abstract

BACKGROUND: Few concepts are as fundamental to plastic surgery as scarring, yet swelling within a scar and its adjacent tissues is a common observation which is not well understood. Mechanical forces, scar contracture, fibrosis, and lymph stasis have been considered as possible explanations for these edematous-appearing areas, but conclusive evidence of a cause of swelling has not been established. The purpose of this study was to evaluate the possible role of microlymphatic stasis or disruption as a causal factor. PATIENTS AND METHODS: Eleven patients (mean age: 43; range: 15 to 70) with localized swelling in conjunction with linear or curvilinear scars were evaluated, 9 with facial scars and 2 with scars of the chest wall and abdomen. Swelling within the scar had been present for an average of 4.5 years (range: 9 months to 13 years). Two patients had undergone previous Z-plasty revisions to the limbs of their curvilinear scars. Radiocolloid lymphoscintigraphy with technetium-99m Sb2S3 was performed on all patients by single or multiple injection technique into the site of the scar corresponding to local edema.
RESULTS: Following injection, rapid egress of radiotracer was visualized along lymphatic pathways posterior to the scar, with continuation to locoregional nodes in all patients with U-shaped "trapdoor" or linear scar configuration. However, in 8 cases there was no evidence of lymphatic drainage traversing or bridging the scar. In 2 patients with multiple prior Z-plasty revisions to the limbs of curvilinear scars, no visualization of lymph channels across the Z-plasty flaps was apparent. In total, 8 patients were diagnosed with lymphedema of the area adjacent to or enclosed within the scar.
CONCLUSIONS: These findings suggest that undrained lymphatic fluid contributes to the pathogenesis of the raised and swollen tissues seen abutting a U-shaped scar. Furthermore, as lymphatic pathways do not reestablish themselves across scars, attempts at improving lymphatic flow with Z-plasty revisions may not succeed in patients with clinical trapdoor scar deformities. Determination of scar lymphedema can assist in the selection of proper management for patients seeking scar revision.

Entities:  

Mesh:

Year:  2007        PMID: 17589258     DOI: 10.1097/01.sap.0000258449.23979.3f

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  6 in total

1.  Functional recovery of fluid drainage precedes lymphangiogenesis in acute murine foreleg lymphedema.

Authors:  Uziel Mendez; Emily M Brown; Emily L Ongstad; Justin R Slis; Jeremy Goldman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-03-16       Impact factor: 4.733

2.  Postrhinoplasty fibrotic syndrome.

Authors:  R P Gruber; M G Galvez; D D Ulvila
Journal:  HNO       Date:  2018-01       Impact factor: 1.284

3.  Fibrosis worsens chronic lymphedema in rodent tissues.

Authors:  Laura L Lynch; Uziel Mendez; Anna B Waller; Amani A Gillette; Roger J Guillory; Jeremy Goldman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-03-13       Impact factor: 4.733

4.  Analysis of blood and lymph vascularization patterns in tissue-engineered human dermo-epidermal skin analogs of different pigmentation.

Authors:  Agnieszka S Klar; Sophie Böttcher-Haberzeth; Thomas Biedermann; Clemens Schiestl; Ernst Reichmann; Martin Meuli
Journal:  Pediatr Surg Int       Date:  2014-02       Impact factor: 1.827

5.  A chronic and latent lymphatic insufficiency follows recovery from acute lymphedema in the rat foreleg.

Authors:  Uziel Mendez; Emily M Stroup; Laura L Lynch; Anna B Waller; Jeremy Goldman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-08-31       Impact factor: 4.733

6.  Long-term Results of Microvascular Lymph Node Transfer: Correlation of Preoperative Factors and Operation Outcome.

Authors:  Eeva H Rannikko; Sinikka H Suominen; Anne M Saarikko; Tiina P Viitanen; Maija T Mäki; Marko P Seppänen; Erkki A Suominen; Pauliina Hartiala
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-01-22
  6 in total

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