Literature DB >> 17588491

Reduction in heavy drinking as a treatment outcome in alcohol dependence.

David R Gastfriend1, James C Garbutt, Helen M Pettinati, Robert F Forman.   

Abstract

In the field of clinical alcohol disorders treatment in North America, abstinence continues to be largely viewed as the optimal treatment goal; however, there is a growing awareness of limitations when abstinence is considered the only successful outcome. Although this issue has been discussed in research settings, new studies on the public health significance of heavy drinking (defined as five or more standard drinks per drinking day in men, and four or more standard drinks per drinking day in women) in the past 10 years suggest that clinical providers should consider the value of alternative outcomes besides abstinence. A focus on abstinence as the primary outcome fails to capture the impact of treatment on reduction in the pattern and in the frequency of alcohol consumption. In addition, evaluating reduction in drinking as "positive" has value for patients as an indicator of clinical progress. Measurement of continuous variables, such as the quantity and the frequency of alcohol consumption, has provided a clearer understanding of the scope of alcohol-related morbidity and mortality at the societal level, and of the relationship between individual patient characteristics and the naturalistic course of alcohol use, abuse, and dependence. A review of these characteristics suggests that there are clinical benefits associated with reducing heavy drinking in alcohol-dependent patients. Given the significant public health consequences associated with heavy drinking and the benefits associated with its reduction, it is proposed that researchers, public health professionals, and clinicians consider using reduction in heavy drinking as a meaningful clinical indicator of treatment response, and that outcomes be individualized to patients' goals and readiness to change.

Entities:  

Mesh:

Year:  2007        PMID: 17588491     DOI: 10.1016/j.jsat.2006.09.008

Source DB:  PubMed          Journal:  J Subst Abuse Treat        ISSN: 0740-5472


  40 in total

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6.  The effects of drinking goal on treatment outcome for alcoholism.

Authors:  Spencer Bujarski; Stephanie S O'Malley; Katy Lunny; Lara A Ray
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7.  The Many Levels of Relapse to Drinking: Commentary on Meyerhoff and Durazzo (ACER 2020).

Authors:  Edith V Sullivan
Journal:  Alcohol Clin Exp Res       Date:  2020-07-26       Impact factor: 3.455

8.  Assessing drug use during follow-up: direct comparison of candidate outcome definitions in pooled analyses of addiction treatment studies.

Authors:  Jeffrey E Korte; Kathryn M Magruder; Codruta C Chiuzan; Sarah L Logan; Therese Killeen; Dipankar Bandyopadhyay; Kathleen T Brady
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9.  Drinking Status Between Ages 50 and 55 for Men From the San Diego Prospective Study Who Developed DSM-IV Alcohol Abuse or Dependence in Prior Follow-Ups.

Authors:  Priscila Dib Gonçalves; Marc A Schuckit; Tom L Smith
Journal:  J Stud Alcohol Drugs       Date:  2017-07       Impact factor: 2.582

10.  Effect of extended-release naltrexone (XR-NTX) on quality of life in alcohol-dependent patients.

Authors:  Helen M Pettinati; David R Gastfriend; Qunming Dong; Henry R Kranzler; Stephanie S O'Malley
Journal:  Alcohol Clin Exp Res       Date:  2008-11-25       Impact factor: 3.455

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