The effect of fasting in Ramadan on hemostatic variables.

Hemostatic measurements were performed in 33 volunteers in the morning and afternoon in one day during the Muslim fasting month of Ramadan, and were then repeated on an ordinary nonfasting day. There were no significant diurnal fluctuations in plasmatic hemostatic parameters either in Ramadan or on a nonfasting day. There was no difference in the morning and afternoon platelet aggregation responses between Ramadan and the nonfasting period. However, aggregation responses to ADP (2 microM/L), adrenaline, collagen, and arachidonic acid were diminished during Ramadan as compared to the nonfasting day. It is concluded that the stress encountered during the Ramadan fast, as depicted in the platelet aggregation responses, is less than that encountered on an ordinary nonfasting day.