Literature DB >> 17586571

Nanoscale shear deformation mechanisms of opposing cartilage aggrecan macromolecules.

Lin Han1, Delphine Dean, Pan Mao, Christine Ortiz, Alan J Grodzinsky.   

Abstract

The nanoscale shear deformation behavior of two opposing end-grafted aggrecan layers was studied in aqueous solutions using atomic force microscopy, and was observed to depend markedly on bath ionic strength, the presence of calcium ions, and the applied lateral displacement rate. These results provide molecular-level insights into the contribution of aggrecan deformation mechanisms to cartilage tissue-level material properties.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17586571      PMCID： PMC1948065          DOI： 10.1529/biophysj.107.114025

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  9 in total

1.  The osmotic pressure of chondroitin sulphate solutions: experimental measurements and theoretical analysis.

Authors:  S Ehrlich; N Wolff; R Schneiderman; A Maroudas; K H Parker; C P Winlove
Journal:  Biorheology       Date:  1998 Nov-Dec       Impact factor: 1.875

Review 2.  Proteoglycans: many forms and many functions.

Authors:  T E Hardingham; A J Fosang
Journal:  FASEB J       Date:  1992-02-01       Impact factor: 5.191

3.  Interaction of proteoglycans and chondroitin sulfates with calcium or phosphate ions.

Authors:  E A MacGregor; J M Bowness
Journal:  Can J Biochem       Date:  1971-04

4.  Lateral nanomechanics of cartilage aggrecan macromolecules.

Authors:  Lin Han; Delphine Dean; Christine Ortiz; Alan J Grodzinsky
Journal:  Biophys J       Date:  2006-12-01       Impact factor: 4.033

5.  Compressive nanomechanics of opposing aggrecan macromolecules.

Authors:  Delphine Dean; Lin Han; Alan J Grodzinsky; Christine Ortiz
Journal:  J Biomech       Date:  2005-11-09       Impact factor: 2.712

6.  The biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior.

Authors:  L A Setton; W Zhu; V C Mow
Journal:  J Biomech       Date:  1993 Apr-May       Impact factor: 2.712

7.  The theoretical distributions and diffusivities of small ions in chondroitin sulphate and hyaluronate.

Authors:  K H Parker; C P Winlove; A Maroudas
Journal:  Biophys Chem       Date:  1988-12       Impact factor: 2.352

8.  The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension.

Authors:  A J Grodzinsky; V Roth; E Myers; W D Grossman; V C Mow
Journal:  J Biomech Eng       Date:  1981-11       Impact factor: 2.097

9.  Binding of calcium to glycosaminoglycans: an equilibrium dialysis study.

Authors:  G K Hunter; K S Wong; J J Kim
Journal:  Arch Biochem Biophys       Date:  1988-01       Impact factor: 4.013
  9 in total
  10 in total

1.  Cartilage aggrecan can undergo self-adhesion.

Authors:  Lin Han; Delphine Dean; Laura A Daher; Alan J Grodzinsky; Christine Ortiz
Journal:  Biophys J       Date:  2008-08-01       Impact factor: 4.033

Review 2.  Aggrecan, an unusual polyelectrolyte: review of solution behavior and physiological implications.

Authors:  Preethi L Chandran; Ferenc Horkay
Journal:  Acta Biomater       Date:  2011-08-17       Impact factor: 8.947

3.  Probing Interactions between Aggrecan and Mica Surface by the Atomic Force Microscopy.

Authors:  Preethi L Chandran; Emilios K Dimitriadis; Peter J Basser; Ferenc Horkay
Journal:  J Polym Sci B Polym Phys       Date:  2010-12-15

4.  Age-related nanostructural and nanomechanical changes of individual human cartilage aggrecan monomers and their glycosaminoglycan side chains.

Authors:  Hsu-Yi Lee; Lin Han; Peter J Roughley; Alan J Grodzinsky; Christine Ortiz
Journal:  J Struct Biol       Date:  2012-12-25       Impact factor: 2.867

5.  Time-dependent nanomechanics of cartilage.

Authors:  Lin Han; Eliot H Frank; Jacqueline J Greene; Hsu-Yi Lee; Han-Hwa K Hung; Alan J Grodzinsky; Christine Ortiz
Journal:  Biophys J       Date:  2011-04-06       Impact factor: 4.033

6.  Single-Molecule Stretching Shows Glycosylation Sets Tension in the Hyaluronan-Aggrecan Bottlebrush.

Authors:  Sarah N Innes-Gold; John P Berezney; Omar A Saleh
Journal:  Biophys J       Date:  2020-08-20       Impact factor: 4.033

7.  Cartilage stress-relaxation is affected by both the charge concentration and valence of solution cations.

Authors:  R K June; K L Mejia; J R Barone; D P Fyhrie
Journal:  Osteoarthritis Cartilage       Date:  2008-10-10       Impact factor: 6.576

8.  Nanomechanics of the Cartilage Extracellular Matrix.

Authors:  Lin Han; Alan J Grodzinsky; Christine Ortiz
Journal:  Annu Rev Mater Res       Date:  2011-07-01       Impact factor: 16.286

9.  Normal and shear interactions between hyaluronan-aggrecan complexes mimicking possible boundary lubricants in articular cartilage in synovial joints.

Authors:  Jasmine Seror; Yulia Merkher; Nir Kampf; Lisa Collinson; Anthony J Day; Alice Maroudas; Jacob Klein
Journal:  Biomacromolecules       Date:  2012-11-01       Impact factor: 6.988

10.  Molecular adhesion between cartilage extracellular matrix macromolecules.

Authors:  Fredrick P Rojas; Michael A Batista; C Alexander Lindburg; Delphine Dean; Alan J Grodzinsky; Christine Ortiz; Lin Han
Journal:  Biomacromolecules       Date:  2014-02-14       Impact factor: 6.988
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.