Literature DB >> 17586318

HIV-1 protease: structure, dynamics, and inhibition.

John M Louis1, Rieko Ishima, Dennis A Torchia, Irene T Weber.   

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Year:  2007        PMID： 17586318     DOI： 10.1016/S1054-3589(07)55008-8

Source DB:  PubMed          Journal:  Adv Pharmacol        ISSN： 1054-3589


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  55 in total

1.  Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.

Authors:  Yu-Chung E Chang; XiaXia Yu; Ying Zhang; Yunfeng Tie; Yuan-Fang Wang; Sofiya Yashchuk; Arun K Ghosh; Robert W Harrison; Irene T Weber
Journal:  J Med Chem       Date:  2012-03-22       Impact factor: 7.446

2.  Transition states of native and drug-resistant HIV-1 protease are the same.

Authors:  D Randal Kipp; Jennifer S Hirschi; Aya Wakata; Harris Goldstein; Vern L Schramm
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-09       Impact factor: 11.205

Review 3.  HIV-1 assembly, budding, and maturation.

Authors:  Wesley I Sundquist; Hans-Georg Kräusslich
Journal:  Cold Spring Harb Perspect Med       Date:  2012-07       Impact factor: 6.915

4.  Spin labeling and Double Electron-Electron Resonance (DEER) to Deconstruct Conformational Ensembles of HIV Protease.

Authors:  Thomas M Casey; Gail E Fanucci
Journal:  Methods Enzymol       Date:  2015-09-01       Impact factor: 1.600

Review 5.  Authentic HIV-1 integrase inhibitors.

Authors:  Chenzhong Liao; Christophe Marchand; Terrence R Burke; Yves Pommier; Marc C Nicklaus
Journal:  Future Med Chem       Date:  2010-07       Impact factor: 3.808

6.  Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease.

Authors:  Jane M Sayer; Fengling Liu; Rieko Ishima; Irene T Weber; John M Louis
Journal:  J Biol Chem       Date:  2008-02-15       Impact factor: 5.157

7.  Pressure-induced structural transition of mature HIV-1 protease from a combined NMR/MD simulation approach.

Authors:  Julien Roche; John M Louis; Ad Bax; Robert B Best
Journal:  Proteins       Date:  2015-10-16

8.  Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir.

Authors:  Hironori Hayashi; Nobutoki Takamune; Takashi Nirasawa; Manabu Aoki; Yoshihiko Morishita; Debananda Das; Yasuhiro Koh; Arun K Ghosh; Shogo Misumi; Hiroaki Mitsuya
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-04       Impact factor: 11.205

9.  Interactions of different inhibitors with active-site aspartyl residues of HIV-1 protease and possible relevance to pepsin.

Authors:  Jane M Sayer; John M Louis
Journal:  Proteins       Date:  2009-05-15

10.  Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site.

Authors:  Oksana Gerlits; Troy Wymore; Amit Das; Chen-Hsiang Shen; Jerry M Parks; Jeremy C Smith; Kevin L Weiss; David A Keen; Matthew P Blakeley; John M Louis; Paul Langan; Irene T Weber; Andrey Kovalevsky
Journal:  Angew Chem Int Ed Engl       Date:  2016-03-09       Impact factor: 15.336
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