OBJECTIVE: A broad spectrum of endocrine and biochemical disturbances was observed in patients with anorexia nervosa. In addition, metabolic changes may concern the efficiency of mitochondrial energy generating system. In our study we analyzed the activities of respiratory chain complexes in females with anorexia nervosa. METHOD: The activities of respiratory chain complexes I, II, IV, I + III, and citrate synthase serving as the control enzyme were measured spectrophotometrically in isolated platelets in 36 females with anorexia nervosa (BMI 15 +/- 1.7) at the age 18-35 years and in 37 age related female controls (BMI 21 +/- 2.2). RESULTS: In females with anorexia nervosa, the activities of respiratory chain complexes I and II in isolated platelets were significantly higher in comparison with controls. No differences were found in the activities of complexes IV and I + III and citrate synthase. CONCLUSION: Our results suggest higher efficiency of some respiratory chain complexes in platelets in females with anorexia nervosa. (c) 2007 by Wiley Periodicals, Inc.
OBJECTIVE: A broad spectrum of endocrine and biochemical disturbances was observed in patients with anorexia nervosa. In addition, metabolic changes may concern the efficiency of mitochondrial energy generating system. In our study we analyzed the activities of respiratory chain complexes in females with anorexia nervosa. METHOD: The activities of respiratory chain complexes I, II, IV, I + III, and citrate synthase serving as the control enzyme were measured spectrophotometrically in isolated platelets in 36 females with anorexia nervosa (BMI 15 +/- 1.7) at the age 18-35 years and in 37 age related female controls (BMI 21 +/- 2.2). RESULTS: In females with anorexia nervosa, the activities of respiratory chain complexes I and II in isolated platelets were significantly higher in comparison with controls. No differences were found in the activities of complexes IV and I + III and citrate synthase. CONCLUSION: Our results suggest higher efficiency of some respiratory chain complexes in platelets in females with anorexia nervosa. (c) 2007 by Wiley Periodicals, Inc.
Authors: Jana Ježková; Viktória Ďurovcová; Laszlo Wenchich; Hana Hansíková; Jiří Zeman; Václav Hána; Josef Marek; Zdeňka Lacinová; Martin Haluzík; Michal Kršek Journal: Diabetes Metab Syndr Obes Date: 2019-08-19 Impact factor: 3.168
Authors: Martina Zvěřová; Jana Hroudová; Zdeněk Fišar; Hana Hansíková; Lucie Kališová; Eva Kitzlerová; Alena Lambertová; Jiří Raboch Journal: Neuropsychiatr Dis Treat Date: 2019-01-14 Impact factor: 2.570