Literature DB >> 17584481

Numerical simulation of an axial blood pump.

Leok Poh Chua1, Boyang Su, Tau Meng Lim, Tongming Zhou.   

Abstract

The axial blood pump with a magnetically suspended impeller is superior to other artificial blood pumps because of its small size. In this article, the distributions of velocity, path line, pressure, and shear stress in the straightener, the rotor, and the diffuser of the axial blood pump, as well as the gap zone were obtained using the commercial software, Fluent (version 6.2). The main focus was on the flow field of the blood pump. The numerical results showed that the axial blood pump could produce 5.14 L/min of blood at 100 mm Hg through the outlet when rotating at 11,000 rpm. However, there was a leakage flow of 1.06 L/min in the gap between the rotor cylinder and the pump housing, and thus the overall flow rate the impeller could generate was 6.2 L/min. The numerical results showed that 75% of the scalar shear stresses (SSs) were less than 250 Pa, and 10% were higher than 500 Pa within the whole pump. The high SS region appeared around the blade tip where a large variation of velocity direction and magnitude was found, which might be due to the steep angle variation at the blade tip. Because the exposure time of the blood cell at the high SS region within the pump was relatively short, it might not cause serious damage to the blood cells, but the improvement of blade profile should be considered in the future design of the axial pump.

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Year:  2007        PMID: 17584481     DOI: 10.1111/j.1525-1594.2007.00422.x

Source DB:  PubMed          Journal:  Artif Organs        ISSN: 0160-564X            Impact factor:   3.094


  9 in total

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3.  Acquired von Willebrand syndrome in patients with extracorporeal life support (ECLS).

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4.  A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index.

Authors:  Katharine H Fraser; Tao Zhang; M Ertan Taskin; Bartley P Griffith; Zhongjun J Wu
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Authors:  Zengsheng Chen; Sofen K Jena; Guruprasad A Giridharan; Steven C Koenig; Mark S Slaughter; Bartley P Griffith; Zhongjun J Wu
Journal:  Int J Numer Method Biomed Eng       Date:  2017-10-06       Impact factor: 2.747

Review 6.  Occlusive thrombosis in arteries.

Authors:  Dongjune Kim; Christopher Bresette; Zixiang Liu; David N Ku
Journal:  APL Bioeng       Date:  2019-11-19

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Authors:  Oanh L Pham; Samuel E Feher; Quoc T Nguyen; Dimitrios V Papavassiliou
Journal:  Sci Rep       Date:  2022-01-07       Impact factor: 4.996

8.  Computations of the shear stresses distribution experienced by passive particles as they circulate in turbulent flow: A case study for vWF protein molecules.

Authors:  Oanh L Pham; Samuel E Feher; Quoc T Nguyen; Dimitrios V Papavassiliou
Journal:  PLoS One       Date:  2022-08-29       Impact factor: 3.752

Review 9.  Antithrombotic therapy in ventricular assist device (VAD) management: From ancient beliefs to updated evidence. A narrative review.

Authors:  Nuccia Morici; Marisa Varrenti; Dario Brunelli; Enrico Perna; Manlio Cipriani; Enrico Ammirati; Maria Frigerio; Marco Cattaneo; Fabrizio Oliva
Journal:  Int J Cardiol Heart Vasc       Date:  2018-06-30
  9 in total

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