Xu Xiong1, Pierre Buekens, Gabriella Pridjian, William D Fraser. 1. Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, Tidewater Building, Suite 2022, SL-18, 1440 Canal Street, New Orleans, LA 70112, USA. xxiong@tulane.edu
Abstract
OBJECTIVE: To examine the association between pregnancy-induced hypertension (PIH) and perinatal mortality. STUDY DESIGN: A population-based, retrospective, cohort study was conducted based on 16,936 pregnancies delivered between January 1, 1989, and December 31, an infant 1990, in Suzhou, China. PIH growth was classified as gestational hypertension, preeclampsia or severe preeclampsia. RESULTS: The perinatal mortality was 10.2 per thousand in normotensive women, 10.3 per thousand in women with gestational hypertension, 17.8 per thousand in women with preeclampsia and 37.0 per thousand in women with severe preeclampsia. Severe preeclampsia was associated with 3.4-fold increased perinatal mortality. After stratifying by intrauterine growth restriction status, if infants were not intrauterine growth restricted, all types of PIH were not associated with increased perinatal mortality. However, when infants were intrauterine growth restricted, all types of PIH were associated with markedly increased perinatal mortality (e.g., 15-fold increased mortality for severe preeclampsia). CONCLUSION: Intrauterine growth restriction secondary to PIH is associated with significantly increased perinatal mortality.
OBJECTIVE: To examine the association between pregnancy-induced hypertension (PIH) and perinatal mortality. STUDY DESIGN: A population-based, retrospective, cohort study was conducted based on 16,936 pregnancies delivered between January 1, 1989, and December 31, an infant 1990, in Suzhou, China. PIH growth was classified as gestational hypertension, preeclampsia or severe preeclampsia. RESULTS: The perinatal mortality was 10.2 per thousand in normotensive women, 10.3 per thousand in women with gestational hypertension, 17.8 per thousand in women with preeclampsia and 37.0 per thousand in women with severe preeclampsia. Severe preeclampsia was associated with 3.4-fold increased perinatal mortality. After stratifying by intrauterine growth restriction status, if infants were not intrauterine growth restricted, all types of PIH were not associated with increased perinatal mortality. However, when infants were intrauterine growth restricted, all types of PIH were associated with markedly increased perinatal mortality (e.g., 15-fold increased mortality for severe preeclampsia). CONCLUSION: Intrauterine growth restriction secondary to PIH is associated with significantly increased perinatal mortality.
Authors: Fahrettin Kılıç; Yasemin Kayadibi; Mehmet Aytaç Yüksel; İbrahim Adaletli; Fethi Emre Ustabaşıoğlu; Mahmut Öncül; Rıza Madazlı; Mehmet Halit Yılmaz; İsmail Mihmanlı; Fatih Kantarcı Journal: Diagn Interv Radiol Date: 2015 May-Jun Impact factor: 2.630
Authors: Anna A Usynina; Andrej M Grjibovski; Alexandra Krettek; Jon Øyvind Odland; Alexander V Kudryavtsev; Erik Eik Anda Journal: Glob Health Action Date: 2017 Impact factor: 2.640
Authors: Tao Xiong; Yi Mu; Juan Liang; Jun Zhu; Xiaohong Li; Jinke Li; Zheng Liu; Yi Qu; Yanping Wang; Dezhi Mu Journal: Bull World Health Organ Date: 2018-06-12 Impact factor: 9.408