[Primary prevention of cervical carcinoma].

Cervical carcinoma is on second place of all tumors related deaths in the world. Cervical carcinomas affects around 500000 of women in the world, out of which 350000 dies every year. It is determined that HPV infection is the cause of cervical carcinoma. For primary prevention of cervical carcinoma there are currently two vaccines. They are suitable for use against HPV types 16 and 18 and additionally against type 6 and 11. Clinical studies till now showed great safety, immunogenity and 100% efficiency against HPV infections and dysplasia. Besides, the vaccine proved to be partially effective against HPV types 45 and 31. The primarily goal of prophylaxis is targeted towards the young girls between age 9 and 17 years. If the vaccine is effective in young males still needs to be determined.