Reflections on science, judgment, and value in evidence-based decision making: a conversation with David Eddy by Sean R. Tunis.

Evidence-based medicine (EBM) has increasingly influenced decision making in health policy and patient care. Appropriate use of EBM in decision making requires a clear understanding of the distinct "anatomical" components of all decisions: (1) scientific evidence and (2) judgments applied to that evidence by individuals or organizations. In this interview, Sean Tunis discusses these principles with David Eddy. Tunis has provided leadership at the national level in applying EBM principles to health policy decision making at the Office of Technology Assessment, the Centers for Medicare and Medicaid Services, and now the Center for Medical Technology Policy. Eddy is cofounder and medical director of Archimedes; he is widely recognized as a seminal contributor to evidence-based medicine, helping shape the initial ideas and applying them to guidelines, coverage policies, and performance measures.