Literature DB >> 17577479

Legionnaires' disease among residents of a long-term care facility: the sentinel event in a community outbreak.

Christina R Phares1, Elaine Russell, Michael C Thigpen, William Service, Matthew B Crist, Martha Salyers, Jeffrey Engel, Robert F Benson, Barry Fields, Matthew R Moore.   

Abstract

BACKGROUND: A long-term care facility (LTCF) reported an outbreak of Legionnaires' disease (LD) in September 2004.
METHODS: We conducted case finding through enhanced surveillance, medical record review (n = 131), and community surveys (n = 258). We cultured water samples from the LTCF and assayed their outdoor air-intake filters for Legionella DNA. We also investigated a cooling tower, the only nearby outdoor aerosol source.
RESULTS: Among 7 confirmed cases, 2 LTCF residents never exited, and 2 community residents never entered the LTCF during the incubation period. Among 63 water and biofilm samples collected from throughout the LTCF, we found no evidence of Legionella colonization, either in the potable water or air-handling systems. Conversely, we isolated a common outbreak-causing strain of Legionella pneumophila serogroup 1 from an industrial cooling tower located 0.4 km from the LTCF and recovered L pneumophila DNA from the LTCF's outdoor air-intake filters, suggesting that aerosolized Legionella from the cooling tower most likely entered the LTCF through the air-intake system or, possibly, through open windows.
CONCLUSION: Residents of LTCFs can acquire LD from community sources. A cluster of LD cases among LTCF residents does not necessarily indicate transmission from within the LTCF.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17577479     DOI: 10.1016/j.ajic.2006.09.014

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  10 in total

Review 1.  Multi-Scale Airborne Infectious Disease Transmission.

Authors:  Charles F Dillon; Michael B Dillon
Journal:  Appl Environ Microbiol       Date:  2020-12-04       Impact factor: 4.792

Review 2.  Current and emerging Legionella diagnostics for laboratory and outbreak investigations.

Authors:  Jeffrey W Mercante; Jonas M Winchell
Journal:  Clin Microbiol Rev       Date:  2015-01       Impact factor: 26.132

3.  Role of Atypical Bacteria in Hospitalized Patients With Nursing Home-Acquired Pneumonia.

Authors:  Laura Meyer-Junco
Journal:  Hosp Pharm       Date:  2016-10

4.  Legionnaires' disease case-finding algorithm, attack rates, and risk factors during a residential outbreak among older adults: an environmental and cohort study.

Authors:  Benjamin J Silk; Jennifer L Foltz; Kompan Ngamsnga; Ellen Brown; Mary Grace Muñoz; Lee M Hampton; Kara Jacobs-Slifka; Natalia A Kozak; J Michael Underwood; John Krick; Tatiana Travis; Olivia Farrow; Barry S Fields; David Blythe; Lauri A Hicks
Journal:  BMC Infect Dis       Date:  2013-06-27       Impact factor: 3.090

5.  Large outbreak of Legionnaires' disease and Pontiac fever at a military base.

Authors:  J Ambrose; L M Hampton; K E Fleming-Dutra; C Marten; C McClusky; C Perry; N A Clemmons; Z McCormic; S Peik; J Mancuso; E Brown; N Kozak; T Travis; C Lucas; B Fields; L Hicks; S B Cersovsky
Journal:  Epidemiol Infect       Date:  2014-11       Impact factor: 4.434

Review 6.  Epidemiology and Ecology of Opportunistic Premise Plumbing Pathogens: Legionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa.

Authors:  Joseph O Falkinham; Elizabeth D Hilborn; Matthew J Arduino; Amy Pruden; Marc A Edwards
Journal:  Environ Health Perspect       Date:  2015-03-20       Impact factor: 9.031

Review 7.  Roles of sunlight and natural ventilation for controlling infection: historical and current perspectives.

Authors:  R A Hobday; S J Dancer
Journal:  J Hosp Infect       Date:  2013-06-20       Impact factor: 3.926

8.  Rapid clinical diagnosis of Legionnaires' disease during the "herald wave" of the swine influenza (H1N1) pandemic: the Legionnaires' disease triad.

Authors:  Burke A Cunha; Nardeen Mickail; Uzma Syed; Stephanie Strollo; Marianne Laguerre
Journal:  Heart Lung       Date:  2010 May-Jun       Impact factor: 2.210

Review 9.  Legionnaires' disease: clinical differentiation from typical and other atypical pneumonias.

Authors:  Burke A Cunha
Journal:  Infect Dis Clin North Am       Date:  2010-03       Impact factor: 5.982

10.  A culture-proven case of community-acquired legionella pneumonia apparently classified as nosocomial: diagnostic and public health implications.

Authors:  Annalisa Bargellini; Isabella Marchesi; Patrizia Marchegiano; Luca Richeldi; Roberto Cagarelli; Greta Ferranti; Paola Borella
Journal:  Case Rep Med       Date:  2013-02-11
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.