Literature DB >> 17576830

Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.

Vivek Swarup1, Joydeep Ghosh, Soumya Ghosh, Amit Saxena, Anirban Basu.   

Abstract

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

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Year:  2007        PMID： 17576830      PMCID： PMC2043228          DOI： 10.1128/AAC.00041-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

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10.  Japanese encephalitis-a pathological and clinical perspective.

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