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Literature DB >> 17576561

Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.

Panagiotis Tsirigotis¹, George Mantzios, Vassiliki Pappa, Konstantinos Girkas, George Salamalekis, Angellos Koutras, Vassiliki Giannopoulou, Konstantina Spirou, Alexia Balanika, Sotirios Papageorgiou, Anthi Travlou, John Dervenoulas.

Abstract

Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.

Entities: Disease Species

Mesh：

Year: 2007 PMID： 17576561 DOI： 10.1007/s00296-007-0386-6

Source DB: PubMed Journal: Rheumatol Int ISSN： 0172-8172 Impact factor: 2.631

26 in total

1. Catastrophic antiphospholipid syndrome: response to repeated plasmapheresis over three years.

Authors: C M Neuwelt; D I Daikh; J A Linfoot; D A Pfister; R G Young; R L Webb; S S London; R A Asherson
Journal: Arthritis Rheum Date: 1997-08

2. The HELLP syndrome at 16 weeks gestation: possible association with the antiphospholipid syndrome.

Authors: L P McMahon; J Smith
Journal: Aust N Z J Obstet Gynaecol Date: 1997-08 Impact factor: 2.100

3. A study of 75 pregnancies in patients with antiphospholipid syndrome.

Authors: D L Huong; B Wechsler; O Bletry; D Vauthier-Brouzes; G Lefebvre; J C Piette
Journal: J Rheumatol Date: 2001-09 Impact factor: 4.666

4. Hepatic infarction in preeclampsia as part of the HELLP syndrome: CT appearance.

Authors: R Zissin; D Yaffe; M Fejgin; D Olsfanger; M Shapiro-Feinberg
Journal: Abdom Imaging Date: 1999 Nov-Dec

5. An association between refractory HELLP syndrome and antiphospholipid antibodies during pregnancy; a report of 2 cases.

Authors: M H Ornstein; J H Rand
Journal: J Rheumatol Date: 1994-07 Impact factor: 4.666

6. Hepatic infarctions during pregnancy are associated with the antiphospholipid syndrome and in addition with complete or incomplete HELLP syndrome.

Authors: R Pauzner; M Dulitzky; H Carp; H Mayan; R Kenett; Z Farfel; A Many
Journal: J Thromb Haemost Date: 2003-08 Impact factor: 5.824

7. Acute renal failure complicating HELLP syndrome, SLE and anti-phospholipid syndrome: successful outcome using plasma exchange therapy.

Authors: G Roberts; M M Gordon; D Porter; A G Jardine; I W Gibson
Journal: Lupus Date: 2003 Impact factor: 2.911

8. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

Authors: B M Sibai; M K Ramadan; I Usta; M Salama; B M Mercer; S A Friedman
Journal: Am J Obstet Gynecol Date: 1993-10 Impact factor: 8.661

Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.

1. Catastrophic antiphospholipid syndrome: response to repeated plasmapheresis over three years.

2. The HELLP syndrome at 16 weeks gestation: possible association with the antiphospholipid syndrome.

3. A study of 75 pregnancies in patients with antiphospholipid syndrome.

4. Hepatic infarction in preeclampsia as part of the HELLP syndrome: CT appearance.

5. An association between refractory HELLP syndrome and antiphospholipid antibodies during pregnancy; a report of 2 cases.

6. Hepatic infarctions during pregnancy are associated with the antiphospholipid syndrome and in addition with complete or incomplete HELLP syndrome.

7. Acute renal failure complicating HELLP syndrome, SLE and anti-phospholipid syndrome: successful outcome using plasma exchange therapy.

8. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

9. Hepatic infarction during pregnancy complicated by antiphospholipid syndrome.

10. Preeclampsia and liver infarction in early pregnancy associated with the antiphospholipid syndrome.

Review 1. HELLP syndrome and its relation with the antiphospholipid syndrome.

Review 2. The significance and management of thrombocytopenia in antiphospholipid syndrome.

3. HELLP Syndrome at 17 Weeks Gestation: A Rare and Catastrophic Phenomenon.

Review 4. Neonatal effects of maternal antiphospholipid syndrome.

Review 5. Managing pregnancy in inflammatory rheumatological diseases.