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Literature DB >> 17574520

Thrombosis of sinus sagitalis during puerperium caused by thrombophilic gene mutation.

Marina Titlic¹, Sanda Pavelin, Ante Tonkic, Ivana Jukic, Ante Buca, Simun Andelinovic.

Abstract

Cerebral veno-sinus thrombosis (CVT) during puerperium may have fatal consequences. A nonspecific clinical picture must be complete with computed tomography of the brain and digital substract angiography of the brain blood vessels, and, once the clinical diagnosis is confirmed, coagulation tests and genetic analysis of the coagulation factor are to be made as well. Genetic polymorphisms associated with thrombophilia such as factor V Leiden, prothrombin G20210A, MTHFR C677T, ACE and PIA1/A2 may be the cause of the hypercoagulability that results in CVT.

Entities: Disease Gene Mutation

Mesh：

Substances：

Year: 2007 PMID： 17574520 DOI： 10.1007/s11239-007-0061-5

Source DB: PubMed Journal: J Thromb Thrombolysis ISSN： 0929-5305 Impact factor: 2.300

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References

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Thrombosis of sinus sagitalis during puerperium caused by thrombophilic gene mutation.

1. Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems.

2. PIA1/A2 polymorphism of the platelet glycoprotein receptor IIb/IIIIa and its correlation with myocardial infarction: an appraisal.

3. Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms.

4. [Deep cerebral venous system thrombosis: report of two cases].

5. Ischemic stroke in young women: risk of recurrence during subsequent pregnancies. French Study Group on Stroke in Pregnancy.

Review 6. Prognostic indicators in cerebral venous sinus thrombosis.

7. ACE gene polymorphisms influence t-PA-induced brain vessel reopening following ischemic stroke.

8. Cerebral venous sinus thrombosis: a clinical study of 23 cases.

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10. Risk of recurrence of cerebral venous and sinus thrombosis during subsequent pregnancy and puerperium.