| Literature DB >> 17574018 |
Abstract
Stem cells reside in a microenvironment or niche that is critical for stem cell maintenance and regulation. But what happens when a stem cell niche is disrupted? In this issue of Cell, two reports (Walkley et al., 2007a, 2007b) demonstrate in mice that alterations in the niche for hematopoietic stem cells lead to the development of myeloproliferative disease.Entities:
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Year: 2007 PMID： 17574018 DOI： 10.1016/j.cell.2007.05.053
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582