Literature DB >> 17573576

Chronic rhinosinusitis and psoriasis: do mutually exclusive systemic Th1 and Th2 disease patterns exist?

Rashid M Rashid1, Andrew Miller, Joseph M Scianna, James A Stankiewicz.   

Abstract

CONCLUSION: Our results support the theory that chronic rhinosinusitis (CRS) is a systemic Th alteration, the relevance of which is discussed in detail.
OBJECTIVE: CRS imposes a heavy burden on society; however, a reliable CRS therapy has not been found. Developing a better understanding of this pathology will help us in our search for more effective therapies. One question, which is rarely examined, is the possibility of CRS existing as a systemic immune alteration in Th response. Thus, the goal of this study was to examine the occurrence of CRS, a Th2 pathology, with Th1 pathologies such as psoriasis. PATIENTS AND METHODS: This study was performed via a retrospective electronic query of our medical center in regards to patients coded with the respective diagnosis.
RESULTS: Analysis of the data showed that occurrence of CRS rarely coincided with the occurrence of psoriasis and other such Th1 pathologies.

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Year:  2007        PMID: 17573576     DOI: 10.1080/00016480601002054

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  3 in total

1.  Increased risk of psoriasis in patients with chronic rhinosinusitis without nasal polyps: a longitudinal follow-up study using Korean national sample cohort.

Authors:  Hyo Geun Choi; Ho Jun Lee
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-07-27       Impact factor: 2.503

2.  Chronic rhinosinusitis in the setting of other chronic inflammatory diseases.

Authors:  Rakesh K Chandra; David Lin; Bruce Tan; Robin Smolak Tudor; David B Conley; Anju T Peters; Leslie C Grammer; Robert P Schleimer; Robert C Kern
Journal:  Am J Otolaryngol       Date:  2010-09-15       Impact factor: 1.808

3.  Psoriasis Increases the Risk of Sudden Sensorineural Hearing Loss: A Longitudinal Follow Up Study Using a National Sample Cohort.

Authors:  Hyo Geun Choi; Bumjung Park; Seok Min Hong; Il-Seok Park; Sung Kyun Kim
Journal:  Int J Environ Res Public Health       Date:  2020-12-12       Impact factor: 3.390

  3 in total

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