OBJECTIVES: This study evaluated the effects of bright light and melatonin on adaptation to night work on an oil rig in the North Sea. METHODS: Seventeen persons working a schedule of 2 weeks on a 12-hour shift, with the first week on night shift and the second week on day shift (ie, the swing shift schedule) participated. In a randomized controlled crossover design, the shift workers received a placebo, melatonin (3 mg, 1 hour before bedtime), or bright light (30-minute exposure, individually scheduled) during the first 4 days on the night shift and during the first 4 days on the day shift. Subjective and objective measures of sleepiness (Karolinska Sleepiness Scale and a simple serial reaction-time test) and sleep (diary and actigraphy) were recorded. RESULTS: Subjective measures indicated that melatonin modestly reduced sleepiness at work during the day shift and increased sleep by 15-20 minutes per day. Bright light gave values in between those of melatonin and the placebo, but with few significant results. According to the objective measures, bright light improved sleep to a minor degree during the night shift. Hardly any side-effects were reported. CONCLUSIONS:Melatonin and bright light modestly improved sleep and sleepiness in this field study. In well-controlled simulated nightwork studies, both melatonin and bright light are more effective in alleviating sleepiness and sleep problems. The less effect in this field study may be due to competing or conflicting factors present in real life or to an inoptimal timing and duration of the treatments.
RCT Entities:
OBJECTIVES: This study evaluated the effects of bright light and melatonin on adaptation to night work on an oil rig in the North Sea. METHODS: Seventeen persons working a schedule of 2 weeks on a 12-hour shift, with the first week on night shift and the second week on day shift (ie, the swing shift schedule) participated. In a randomized controlled crossover design, the shift workers received a placebo, melatonin (3 mg, 1 hour before bedtime), or bright light (30-minute exposure, individually scheduled) during the first 4 days on the night shift and during the first 4 days on the day shift. Subjective and objective measures of sleepiness (Karolinska Sleepiness Scale and a simple serial reaction-time test) and sleep (diary and actigraphy) were recorded. RESULTS: Subjective measures indicated that melatonin modestly reduced sleepiness at work during the day shift and increased sleep by 15-20 minutes per day. Bright light gave values in between those of melatonin and the placebo, but with few significant results. According to the objective measures, bright light improved sleep to a minor degree during the night shift. Hardly any side-effects were reported. CONCLUSIONS:Melatonin and bright light modestly improved sleep and sleepiness in this field study. In well-controlled simulated nightwork studies, both melatonin and bright light are more effective in alleviating sleepiness and sleep problems. The less effect in this field study may be due to competing or conflicting factors present in real life or to an inoptimal timing and duration of the treatments.
Authors: Michael T Smith; Christina S McCrae; Joseph Cheung; Jennifer L Martin; Christopher G Harrod; Jonathan L Heald; Kelly A Carden Journal: J Clin Sleep Med Date: 2018-07-15 Impact factor: 4.062
Authors: Lauren A Booker; Tracey L Sletten; Maree Barnes; Pasquale Alvaro; Allison Collins; Ching Li Chai-Coetzer; Marcus McMahon; Steven W Lockley; Shantha M W Rajaratnam; Mark E Howard Journal: J Clin Sleep Med Date: 2022-04-01 Impact factor: 4.062
Authors: Tracy E Slanger; J Valérie Gross; Andreas Pinger; Peter Morfeld; Miriam Bellinger; Anna-Lena Duhme; Rosalinde Amancay Reichardt Ortega; Giovanni Costa; Tim R Driscoll; Russell G Foster; Lin Fritschi; Mikael Sallinen; Juha Liira; Thomas C Erren Journal: Cochrane Database Syst Rev Date: 2016-08-23
Authors: Bjørn Bjorvatn; Ståle Pallesen; Siri Waage; Eirunn Thun; Kjersti M Blytt Journal: Scand J Work Environ Health Date: 2020-10-20 Impact factor: 5.024