Literature DB >> 17572662

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family.

E F Lee, P E Czabotar, B J Smith, K Deshayes, K Zobel, P M Colman, W D Fairlie.   

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Year:  2007        PMID： 17572662     DOI： 10.1038/sj.cdd.4402178

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


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  95 in total

1.  Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.

Authors:  Emmanuele Ambrosi; Stefano Capaldi; Michele Bovi; Gianmaria Saccomani; Massimiliano Perduca; Hugo L Monaco
Journal:  Biochem J       Date:  2011-09-01       Impact factor: 3.857

2.  BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Authors:  Jun Wei; John L Stebbins; Shinichi Kitada; Rupesh Dash; William Placzek; Michele F Rega; Bainan Wu; Jason Cellitti; Dayong Zhai; Li Yang; Russell Dahl; Paul B Fisher; John C Reed; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2010-05-27       Impact factor: 7.446

3.  Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis.

Authors:  Peter E Czabotar; Erinna F Lee; Geoff V Thompson; Ahmad Z Wardak; W Douglas Fairlie; Peter M Colman
Journal:  J Biol Chem       Date:  2011-01-03       Impact factor: 5.157

Review 4.  Protein binding specificity versus promiscuity.

Authors:  Gideon Schreiber; Amy E Keating
Journal:  Curr Opin Struct Biol       Date:  2010-11-09       Impact factor: 6.809

5.  Dynamics of the BH3-Only Protein Binding Interface of Bcl-xL.

Authors:  Xiaorong Liu; Alex Beugelsdijk; Jianhan Chen
Journal:  Biophys J       Date:  2015-09-01       Impact factor: 4.033

Review 6.  Ceramide channels and mitochondrial outer membrane permeability.

Authors:  Marco Colombini
Journal:  J Bioenerg Biomembr       Date:  2016-01-22       Impact factor: 2.945

7.  Biophysical basis of the promiscuous binding of B-cell lymphoma protein 2 apoptotic repressor to BH3 ligands.

Authors:  Vikas Bhat; Max B Olenick; Brett J Schuchardt; David C Mikles; Caleb B McDonald; Amjad Farooq
Journal:  J Mol Recognit       Date:  2013-10       Impact factor: 2.137

Review 8.  Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

Authors:  Peter E Czabotar; Guillaume Lessene; Andreas Strasser; Jerry M Adams
Journal:  Nat Rev Mol Cell Biol       Date:  2014-01       Impact factor: 94.444

9.  Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression.

Authors:  Jianfang Chen; Haibin Zhou; Angelo Aguilar; Liu Liu; Longchuan Bai; Donna McEachern; Chao-Yie Yang; Jennifer L Meagher; Jeanne A Stuckey; Shaomeng Wang
Journal:  J Med Chem       Date:  2012-10-02       Impact factor: 7.446

10.  Small-molecule inducible transcriptional control in mammalian cells.

Authors:  Aarti Doshi; Fatemeh Sadeghi; Navin Varadarajan; Patrick C Cirino
Journal:  Crit Rev Biotechnol       Date:  2020-08-30       Impact factor: 8.429
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