Literature DB >> 17572300

Chemotherapy-induced resistance by ATP-binding cassette transporter genes.

Jean-Pierre Gillet1, Thomas Efferth, José Remacle.   

Abstract

A key issue in the treatment of many cancers is the development of resistance to chemotherapeutic drugs. Resistance mechanisms are numerous and complex. One of them is mediated by the overexpression of ATP-binding cassette (ABC) transporters able to efflux drugs out of the tumor cell. The last two decades have seen notable growth of knowledge concerning the involvement of ABC transporters in resistance to chemotherapy. This review emphasizes these transporters, their clinical relevance and the diagnostic methods and strategies to circumvent multidrug resistance (MDR) mediated by ABC transporters.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17572300     DOI： 10.1016/j.bbcan.2007.05.002

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  91 in total

Review 1.  Drug resistance: still a daunting challenge to the successful treatment of AML.

Authors:  Brian C Shaffer; Jean-Pierre Gillet; Chirayu Patel; Maria R Baer; Susan E Bates; Michael M Gottesman
Journal:  Drug Resist Updat       Date:  2012-03-11       Impact factor: 18.500

2.  The ABC of glycosylation.

Authors:  Paola Perego; Laura Gatti; Giovanni L Beretta
Journal:  Nat Rev Cancer       Date:  2010-06-10       Impact factor: 60.716

Review 3.  Nanoparticles: a promising modality in the treatment of sarcomas.

Authors:  Michiro Susa; Lara Milane; Mansoor M Amiji; Francis J Hornicek; Zhenfeng Duan
Journal:  Pharm Res       Date:  2010-05-27       Impact factor: 4.200

4.  Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance.

Authors:  Jean-Pierre Gillet; Anna Maria Calcagno; Sudhir Varma; Miguel Marino; Lisa J Green; Meena I Vora; Chirayu Patel; Josiah N Orina; Tatiana A Eliseeva; Vineet Singal; Raji Padmanabhan; Ben Davidson; Ram Ganapathi; Anil K Sood; Bo R Rueda; Suresh V Ambudkar; Michael M Gottesman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-08       Impact factor: 11.205

Review 5.  Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology.

Authors:  Lara Milane; Shanthi Ganesh; Shruti Shah; Zhen-Feng Duan; Mansoor Amiji
Journal:  J Control Release       Date:  2011-04-08       Impact factor: 9.776

6.  Both maltose-binding protein and ATP are required for nucleotide-binding domain closure in the intact maltose ABC transporter.

Authors:  Cedric Orelle; Tulin Ayvaz; R Michael Everly; Candice S Klug; Amy L Davidson
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-25       Impact factor: 11.205

7.  Resistance mechanisms of cancer cells to the novel vacuolar H(+)-ATPase inhibitor archazolid B.

Authors:  Rebecca Hamm; Yoshikazu Sugimoto; Heinrich Steinmetz; Thomas Efferth
Journal:  Invest New Drugs       Date:  2014-07-29       Impact factor: 3.850

8.  Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.

Authors:  Chun-ling Dai; Amit K Tiwari; Chung-Pu Wu; Xiao-Dong Su; Si-Rong Wang; Dong-geng Liu; Charles R Ashby; Yan Huang; Robert W Robey; Yong-ju Liang; Li-ming Chen; Cheng-Jun Shi; Suresh V Ambudkar; Zhe-Sheng Chen; Li-wu Fu
Journal:  Cancer Res       Date:  2008-10-01       Impact factor: 12.701

9.  Anticancer effect and structure-activity analysis of marine products isolated from metabolites of mangrove fungi in the South China Sea.

Authors:  Li-yang Tao; Jian-ye Zhang; Yong-ju Liang; Li-ming Chen; Li-sheng Zhen; Fang Wang; Yan-jun Mi; Zhi-gang She; Kenneth Kin Wah To; Yong-cheng Lin; Li-wu Fu
Journal:  Mar Drugs       Date:  2010-04-01       Impact factor: 5.118

10.  A survey of integral alpha-helical membrane proteins.

Authors:  Libusha Kelly; Ursula Pieper; Narayanan Eswar; Franklin A Hays; Min Li; Zygy Roe-Zurz; Deanna L Kroetz; Kathleen M Giacomini; Robert M Stroud; Andrej Sali
Journal:  J Struct Funct Genomics       Date:  2009-09-17
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.