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Literature DB >> 17572175

In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked?

De-Maw Chuang¹, Husseini K Manji.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2007 PMID： 17572175 PMCID： PMC1949906 DOI： 10.1016/j.biopsych.2007.04.008

Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382

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27 in total

Review 1. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials.

Authors: Jill Heemskerk; Allan J Tobin; Bernard Ravina
Journal: Nat Neurosci Date: 2002-11 Impact factor: 24.884

2. Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

Authors: M Hong; D C Chen; P S Klein; V M Lee
Journal: J Biol Chem Date: 1997-10-03 Impact factor: 5.157

3. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS.

Authors: G Chen; W Z Zeng; P X Yuan; L D Huang; Y M Jiang; Z H Zhao; H K Manji
Journal: J Neurochem Date: 1999-02 Impact factor: 5.372

Review 4. Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders.

Authors: W C Drevets
Journal: Curr Opin Neurobiol Date: 2001-04 Impact factor: 6.627

5. Enhancement of hippocampal neurogenesis by lithium.

Authors: G Chen; G Rajkowska; F Du; N Seraji-Bozorgzad; H K Manji
Journal: J Neurochem Date: 2000-10 Impact factor: 5.372

6. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

Authors: G J Moore; J M Bebchuk; K Hasanat; G Chen; N Seraji-Bozorgzad; I B Wilds; M W Faulk; S Koch; D A Glitz; L Jolkovsky; H K Manji
Journal: Biol Psychiatry Date: 2000-07-01 Impact factor: 13.382

7. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model.

Authors: Ming Ren; Vladimir V Senatorov; Ren-Wu Chen; De-Maw Chuang
Journal: Proc Natl Acad Sci U S A Date: 2003-05-05 Impact factor: 11.205

8. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

Authors: Haim Einat; Peixiong Yuan; Todd D Gould; Jianling Li; JianHua Du; Lei Zhang; Husseini K Manji; Guang Chen
Journal: J Neurosci Date: 2003-08-13 Impact factor: 6.167

9. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides.

Authors: Christopher J Phiel; Christina A Wilson; Virginia M-Y Lee; Peter S Klein
Journal: Nature Date: 2003-05-22 Impact factor: 49.962

10. Does long-term medication with lithium, clozapine or antidepressants prevent or attenuate dementia in bipolar and depressed patients?

Authors: Jules Angst; Alex Gamma; Regina Gerber-Werder; Carlos A Zarate; Husseini K Manji
Journal: Int J Psychiatry Clin Pract Date: 2007 Impact factor: 1.812

24 in total

1. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression.

Authors: Bhavya Voleti; Keith Q Tanis; Samuel S Newton; Ronald S Duman
Journal: Biol Psychiatry Date: 2011-09-19 Impact factor: 13.382

2. Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study.

Authors: In Kyoon Lyoo; Stephen R Dager; Jieun E Kim; Sujung J Yoon; Seth D Friedman; David L Dunner; Perry F Renshaw
Journal: Neuropsychopharmacology Date: 2010-03-31 Impact factor: 7.853

10. No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS.

Authors: Alan Gill; Joshua Kidd; Fernando Vieira; Kenneth Thompson; Steven Perrin
Journal: PLoS One Date: 2009-08-03 Impact factor: 3.240

In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked?

Review 1. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials.

2. Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

3. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS.

Review 4. Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders.

5. Enhancement of hippocampal neurogenesis by lithium.

6. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

7. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model.

8. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

9. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides.

10. Does long-term medication with lithium, clozapine or antidepressants prevent or attenuate dementia in bipolar and depressed patients?

1. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression.

2. Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study.

Review 3. Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.

4. Pharmacological Management of Anxiety Disorders in the Elderly.

5. Wnt2 expression and signaling is increased by different classes of antidepressant treatments.

6. Lithium increases synaptic GluA2 in hippocampal neurons by elevating the δ-catenin protein.

7. Lithium increases synapse formation between hippocampal neurons by depleting phosphoinositides.

Review 8. The neurotrophic and neuroprotective effects of psychotropic agents.

Review 9. Lithium and cognitive enhancement: leave it or take it?

10. No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS.