Literature DB >> 17570664

Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus.

Jian Lv1, Yunbo Qian, Tingting Liu, Yongmei Wang.   

Abstract

Several representative amphiphilic cationic quinine-derived have been synthesized and evaluated against methicillin- resistant Staphylococcus aureus. This is the first reported antibacterial activity of this class of compounds. In vitro the minimal inhibitory concentration values of the best compound Q7 ranged from 0.4 to 1.6 microg/mL (MBC<3.2 microg/mL).

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Year:  2007        PMID: 17570664     DOI: 10.1016/j.bmcl.2007.05.065

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Natural product-derived quaternary ammonium compounds with potent antimicrobial activity.

Authors:  Maureen D Joyce; Megan C Jennings; Celina N Santiago; Madison H Fletcher; William M Wuest; Kevin Pc Minbiole
Journal:  J Antibiot (Tokyo)       Date:  2015-11-18       Impact factor: 2.649

Review 2.  A review on quinoline derivatives as anti-methicillin resistant Staphylococcus aureus (MRSA) agents.

Authors:  Pradeep Kumar
Journal:  BMC Chem       Date:  2020-03-13

3.  Quinoline Antimalarials Increase the Antibacterial Activity of Ampicillin.

Authors:  Olajumoke A Olateju; Chinedum P Babalola; Olujide O Olubiyi; Olayinka A Kotila; David A Kwasi; Anderson O Oaikhena; Iruka N Okeke
Journal:  Front Microbiol       Date:  2021-06-02       Impact factor: 5.640

  3 in total

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