Literature DB >> 17570445

Acetylated pseudoguaianolides from Parthenium hysterophorus and their cytotoxic activity.

Biswanath Das1, V Saidi Reddy, M Krishnaiah, A V S Sharma, K Ravi Kumar, J Venkateswara Rao, V Sridhar.   

Abstract

Chemical examination of the flowers of Parthenium hysterophorus has resulted in the isolation of four acetylated pseudoguaianolides along with several known constituents. The structures of the compounds were derived from detailed studies of their spectral (1D and 2D NMR and FABMS) data and by comparison of the values with those of parthenin, a major known constituent of the plant. The cytotoxic activity of parthenin and the constituents was evaluated using Jurkat (human: T lymphocyte; acute T cell leukemia), HL-60 (human leukemia) and Hela (human cervical carcinoma) cells.

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Year:  2007        PMID: 17570445     DOI: 10.1016/j.phytochem.2007.05.002

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  5 in total

1.  The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.

Authors:  Jared N Balaich; Derrick K Mathias; Baldwyn Torto; Bryan T Jackson; Dingyin Tao; Babak Ebrahimi; Brian B Tarimo; Xavier Cheseto; Woodbridge A Foster; Rhoel R Dinglasan
Journal:  Antimicrob Agents Chemother       Date:  2016-03-25       Impact factor: 5.191

2.  Harmful and beneficial aspects of Parthenium hysterophorus: an update.

Authors:  Seema Patel
Journal:  3 Biotech       Date:  2011-04-27       Impact factor: 2.406

3.  Green Synthesis of Silver Nanoparticles Using Parthenium Hysterophorus: Optimization, Characterization and In Vitro Therapeutic Evaluation.

Authors:  Anam Ahsan; Muhammad Asim Farooq; Ali Ahsan Bajwa; Amna Parveen
Journal:  Molecules       Date:  2020-07-22       Impact factor: 4.411

4.  Toxic Potential and Metabolic Profiling of Two Australian Biotypes of the Invasive Plant Parthenium Weed (Parthenium hysterophorus L.).

Authors:  Ali Ahsan Bajwa; Paul A Weston; Saliya Gurusinghe; Sajid Latif; Steve W Adkins; Leslie A Weston
Journal:  Toxins (Basel)       Date:  2020-07-10       Impact factor: 4.546

5.  The Invasive American Weed Parthenium hysterophorus Can Negatively Impact Malaria Control in Africa.

Authors:  Vincent O Nyasembe; Xavier Cheseto; Fatma Kaplan; Woodbridge A Foster; Peter E A Teal; James H Tumlinson; Christian Borgemeister; Baldwyn Torto
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240

  5 in total

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