Literature DB >> 17570003

Sacral insufficiency fracture complicated by epidural haematoma and cauda equina syndrome in a patient with multiple myeloma.

Carmel G Cronin1, Derek G Lohan, Ronan Swords, Margaret Murray, Joseph M Murphy, Clare Roche.   

Abstract

We report the case of a patient with multiple myeloma (MM) and extensive lytic bone disease who presented with a short history of back pain and leg weakness. Magnetic resonance imaging (MRI) of the lumbar spine revealed a sacral insufficiency fracture complicated by an epidural haematoma. Bleeding tendency in this case can be accounted for by platelet function defects, often described in plasma cell disorders in the absence of obvious coagulation abnormalities. Surgical intervention was contraindicated as a result of poor overall patient performance status (poor surgical candidate due to extensive myelomatous bone disease, previous vertebral compression fractures requiring orthopaedic stabilisation, and requiring opiate analgesia for bone pain) and management was conservative. Patients presenting with back pain and documented bone disease in the setting of myeloma should be managed with a high index of clinical suspicion and considered for urgent MR imaging to avoid missing this serious and potentially reversible complication. We report the undescribed causative association between sacral insufficiency fracture and lumbo-sacral epidural haematoma. We illustrate the MRI signal and contrast enhancement pattern of an acute presentation of epidural haematoma.

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Year:  2007        PMID: 17570003     DOI: 10.1007/s10140-007-0623-z

Source DB:  PubMed          Journal:  Emerg Radiol        ISSN: 1070-3004


  19 in total

1.  Spinal epidural hematoma associated with Paget's disease.

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Journal:  Surg Neurol       Date:  1988-08

2.  Spinal epidural hematoma with spontaneous recovery demonstrated by magnetic resonance imaging.

Authors:  S Saito; H Katsube; Y Kobayashi
Journal:  Spine (Phila Pa 1976)       Date:  1994-02-15       Impact factor: 3.468

3.  Nontraumatic spinal epidural hematomas. MR features.

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Journal:  Acta Radiol       Date:  1997-01       Impact factor: 1.990

4.  Can spontaneous spinal epidural haematoma be managed safely without operation? A report of four cases.

Authors:  J Duffill; O C Sparrow; J Millar; C S Barker
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-12       Impact factor: 10.154

5.  Sacral insufficiency fractures: an unsuspected cause of low back pain.

Authors:  B Dasgupta; N Shah; H Brown; T E Gordon; A B Tanqueray; J A Mellor
Journal:  Br J Rheumatol       Date:  1998-07

6.  Cervical epidural hematoma secondary to an extradural vascular malformation in an infant: case report.

Authors:  M G Muhonen; J G Piper; S A Moore; A H Menezes
Journal:  Neurosurgery       Date:  1995-03       Impact factor: 4.654

7.  Central gadolinium enhancement of an acute spontaneous spinal epidural haematoma.

Authors:  C J Chen; L S Ro
Journal:  Neuroradiology       Date:  1996-05       Impact factor: 2.804

8.  Spontaneous osteoporotic fracture of the sacrum. An unrecognized syndrome of the elderly.

Authors:  H Lourie
Journal:  JAMA       Date:  1982-08-13       Impact factor: 56.272

9.  MRI of spinal epidural lymphoma.

Authors:  M Mascalchi; P Torselli; F Falaschi; G Dal Pozzo
Journal:  Neuroradiology       Date:  1995-05       Impact factor: 2.804

10.  Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome.

Authors:  M T Lawton; R W Porter; J E Heiserman; R Jacobowitz; V K Sonntag; C A Dickman
Journal:  J Neurosurg       Date:  1995-07       Impact factor: 5.115

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  2 in total

1.  [Role and limitations of vertebroplasty and kyphoplasty in the management of spinal metastases].

Authors:  M Akbar; M Eichler; S Hagmann; B Lehner; S Hemmer; C Kasperk; B Wiedenhöfer
Journal:  Orthopade       Date:  2012-08       Impact factor: 1.087

Review 2.  Fragility fractures of the sacrum: how to identify and when to treat surgically?

Authors:  D Wagner; C Ossendorf; D Gruszka; A Hofmann; P M Rommens
Journal:  Eur J Trauma Emerg Surg       Date:  2015-04-18       Impact factor: 3.693

  2 in total

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