Literature DB >> 17569488

Thyroid gangliosides with high affinity for thyrotropin: potential role in thyroid regulation.

B R Mullin1, T Pacuszka, G Lee, L D Kohn, R O Brady, P H Fishman.   

Abstract

Thyroid cell membranes contain a multiplicity of gangliosides, some of which inhibit thyrotropin binding to thyroid membranes. The most potent inhibitor is a ganglioside which is present in only trace amounts and appears to have a novel structure. Thyroid gangliosides may play a role in relaying the hormonal message to the thyroid cell.

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Year:  1978        PMID： 17569488     DOI： 10.1126/science.199.4324.77

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  Specificities of autoantibodies in autoimmune receptor diseases.

Authors:  M H De Baets
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

2.  Opiates and enkephalins inhibit synthesis of gangliosides and membrane glycoproteins in mouse neuroblastoma cell line N4TG1.

Authors:  G Dawson; R McLawhon; R J Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  Interaction of human chorionic gonadotropin with membrane components of rat testes.

Authors:  T Pacuszka; J C Osborne; R O Brady; P H Fishman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

4.  A specific GT1 ganglioside-luteinizing hormone interaction induces conductance changes in lipid bilayers.

Authors:  P Chatelain; M Deleers; A Poss; J M Ruysschaert
Journal:  Experientia       Date:  1979-03-15

Review 5.  Brain and thymus gangliosides: their molecular diversity and its biological implications and a dynamic annular model for their function in cell surface membranes.

Authors:  Y Nagai; M Iwamori
Journal:  Mol Cell Biochem       Date:  1980-02-08       Impact factor: 3.396

6.  Effect of thyroid phospholipids on the interaction of thyrotropin with thyroid membranes.

Authors:  F Omodeo-Sale; R O Brady; P H Fishman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

7.  Gangliosides and phospholipids in human thyroids responsive and unresponsive to thyrotropin.

Authors:  A Mariano; A Di Carlo; P E Macchia; G Pisano; U Parmeggiani; V Macchia
Journal:  J Endocrinol Invest       Date:  1990-11       Impact factor: 4.256

8.  Monoclonal antibodies to the thyrotropin receptor: stimulating and blocking antibodies derived from the lymphocytes of patients with Graves disease.

Authors:  W A Valente; P Vitti; Z Yavin; E Yavin; C M Rotella; E F Grollman; R S Toccafondi; L D Kohn
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

9.  Effect of gangliosides on phospholipid bilayers: a study with the lipophilic ions relaxation method.

Authors:  C Usai; M Robello; F Gambale; C Marchetti
Journal:  J Membr Biol       Date:  1984       Impact factor: 1.843

10.  Isolation and partial characterization of the neutral glycosphingolipids and gangliosides of the human heart.

Authors:  G M Levis; J N Karli; S D Moulopoulos
Journal:  Lipids       Date:  1979-01       Impact factor: 1.880
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