Literature DB >> 17568952

Alcohol does not affect dark adaptation or luminance increment thresholds.

Sarah A Khan1, Brian Timney.   

Abstract

OBJECTIVE: It has been proposed that alcohol might induce within the retina a state akin to dark adaptation. However, the evidence to support this proposal is quite indirect. Another possibility is that alcohol might affect retinal gain control rather than sensitivity. To investigate these proposals psychophysically, we measured dark adaptation functions and increment thresholds with the increment threshold procedure in individuals with moderate blood alcohol concentrations (BACs).
METHOD: Individuals were tested under both alcohol and no-alcohol conditions (BAC approximately .08%). In Experiment 1, thresholds for the detection of a parafoveal target were measured over a 25-minute period following a 3-minute bleach in six males. In Experiment 2, the cone dark adaptation function of four males was examined in more detail for a foveal target following bleaching at three different levels. In Experiment 3, we measured the thresholds of nine men for a small target superimposed on a background field that varied over 4 log units in luminance.
RESULTS: We found no effects of alcohol on either the rod or the cone portion of the dark adaptation curve or on increment thresholds.
CONCLUSIONS: Together, these data indicate that moderate alcohol ingestion does not affect the recovery of visual sensitivity in the dark nor does it affect gain control at the retinal level.

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Year:  2007        PMID: 17568952     DOI: 10.15288/jsad.2007.68.493

Source DB:  PubMed          Journal:  J Stud Alcohol Drugs        ISSN: 1937-1888            Impact factor:   2.582


  3 in total

1.  Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health.

Authors:  Cynthia Owsley; Carrie Huisingh; Gregory R Jackson; Christine A Curcio; Alexander J Szalai; Nassrin Dashti; Mark Clark; Kia Rookard; Mark A McCrory; Tyler T Wright; Michael A Callahan; Lanning B Kline; C Douglas Witherspoon; Gerald McGwin
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-05-22       Impact factor: 4.799

2.  Differential effects of alcohol on contrast processing mediated by the magnocellular and parvocellular pathways.

Authors:  Xiaohua Zhuang; Andrea King; Patrick McNamara; Joel Pokorny; Dingcai Cao
Journal:  J Vis       Date:  2012-10-22       Impact factor: 2.240

3.  Acute effect of alcohol intake on sine-wave Cartesian and polar contrast sensitivity functions.

Authors:  M K Cavalcanti-Galdino; J A da Silva; L C Mendes; N A da Santos; M L B Simas
Journal:  Braz J Med Biol Res       Date:  2014-03-21       Impact factor: 2.590

  3 in total

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