| Literature DB >> 17568800 |
Kenneth R Feingold1, Matthias Schmuth, Peter M Elias.
Abstract
Disruption of the permeability barrier stimulates a repair response that leads to the restoration of barrier function. Previous studies demonstrated that changes in ions, particularly calcium, and cytokines are positive signals, whereas serine protease activation of proteinase-activated receptor 2 is a negative signal regulating barrier recovery. Ikeyama and colleagues provide data that the nitric oxide signaling pathway also regulates barrier homeostasis.Entities:
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Year: 2007 PMID: 17568800 DOI: 10.1038/sj.jid.5700774
Source DB: PubMed Journal: J Invest Dermatol ISSN: 0022-202X Impact factor: 8.551