Literature DB >> 17568799

FGFR3 mutations in epidermal nevi and seborrheic keratoses: lessons from urothelium and skin.

Christian Hafner1, Arndt Hartmann, Thomas Vogt.   

Abstract

Somatic FGFR3 mutations have been reported in various cancers such as urothelial carcinoma. Evidence is growing that these mutations are also involved in the pathogenesis of benign acanthotic skin tumors such as epidermal nevi and seborrheic keratoses. The report by Hernandez et al. strongly supports this concept. However, further studies are required for a better pathogenetic understanding of FGFR3 related tumors in urothelium and skin.

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Year:  2007        PMID： 17568799     DOI： 10.1038/sj.jid.5700772

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  10 in total

1.  [R248C FGFR3 mutation. Effect on cell growth, apoptosis and attachment in HaCaT keratinocytes].

Authors:  C Hafner; A Hartmann
Journal:  Pathologe       Date:  2010-10       Impact factor: 1.011

2.  UVA induces lesions resembling seborrheic keratoses in mice with keratinocyte-specific PTEN downregulation.

Authors:  Mei Ming; Christopher R Shea; Li Feng; Keyoumars Soltani; Yu-Ying He
Journal:  J Invest Dermatol       Date:  2011-03-10       Impact factor: 8.551

3.  Identification of novel fibroblast growth factor receptor 3 gene mutations in actinic cheilitis and squamous cell carcinoma of the lip.

Authors:  Annie Chou; Nusi Dekker; Richard C K Jordan
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2009-04

4.  Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.

Authors:  James T Bennett; Tiong Yang Tan; Diana Alcantara; Martine Tétrault; Andrew E Timms; Dana Jensen; Sarah Collins; Malgorzata J M Nowaczyk; Marjorie J Lindhurst; Katherine M Christensen; Stephen R Braddock; Heather Brandling-Bennett; Raoul C M Hennekam; Brian Chung; Anna Lehman; John Su; SuYuen Ng; David J Amor; Jacek Majewski; Les G Biesecker; Kym M Boycott; William B Dobyns; Mark O'Driscoll; Ute Moog; Laura M McDonell
Journal:  Am J Hum Genet       Date:  2016-03-03       Impact factor: 11.025

Review 5.  Hypophosphatemia: the common denominator of all rickets.

Authors:  Dov Tiosano; Ze'ev Hochberg
Journal:  J Bone Miner Metab       Date:  2009-06-06       Impact factor: 2.626

6.  Mulberry like growth in the right ear.

Authors:  Mohan H Kudur
Journal:  Indian J Dermatol       Date:  2011-11       Impact factor: 1.494

Review 7.  Mutational analysis of merkel cell carcinoma.

Authors:  Derek J Erstad; James C Cusack
Journal:  Cancers (Basel)       Date:  2014-10-17       Impact factor: 6.639

8.  Seborrheic Keratoses as the First Sign of Bladder Carcinoma: Case Report of Leser-Trélat Sign in a Rare Association with Urinary Tract Cancer.

Authors:  Aline Stollmeier; Bernardo Augusto Rosario; Bruna Loise Mayer; Gibran Avelino Frandoloso; Francisco Luiz Gomide Mafra Magalhães; Gustavo Lenci Marques
Journal:  Case Rep Med       Date:  2016-11-23

9.  RASopathic skin eruptions during vemurafenib therapy.

Authors:  Jeannine D Rinderknecht; Simone M Goldinger; Sima Rozati; Jivko Kamarashev; Katrin Kerl; Lars E French; Reinhard Dummer; Benedetta Belloni
Journal:  PLoS One       Date:  2013-03-14       Impact factor: 3.240

10.  FGFR3 mutation increases bladder tumourigenesis by suppressing acute inflammation.

Authors:  Mona Foth; Nur Faezah Binti Ismail; Jeng Sum Charmaine Kung; Darren Tomlinson; Margaret A Knowles; Pontus Eriksson; Gottfrid Sjödahl; Jonathan M Salmond; Owen J Sansom; Tomoko Iwata
Journal:  J Pathol       Date:  2018-09-19       Impact factor: 7.996
  10 in total

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