OBJECTIVES: The persistence and hyperplasia of the primary vitreous is a rare ocular malformation whose origin remains unknown. The goal of this study was to retrospectively analyze the records of the children followed in our department and to note sex, antecedents, age and reason for the first consultation, side and ocular structures involved, treatment, follow-up, complications, and progression. METHODS: The initial clinical examination was noted and completed by the examination under general anesthesia and the surgical or nonsurgical treatment proposed. RESULTS: Fifty-six eyes of 52 children were included: 19 anterior forms, four posterior, 25 mixed, and eight eyes already operated on in other centers. Fifty eyes had surgical treatment. At the end of follow-up, 13 eyes had a vision equal to or greater than 20/200 (23%) including five that were better than 20/100 (9%). Average follow-up was 32.5 months. CONCLUSIONS: Persistence of the fetal vascular system is a group of complex ocular malformations requiring an early diagnosis and well-adapted management.
OBJECTIVES: The persistence and hyperplasia of the primary vitreous is a rare ocular malformation whose origin remains unknown. The goal of this study was to retrospectively analyze the records of the children followed in our department and to note sex, antecedents, age and reason for the first consultation, side and ocular structures involved, treatment, follow-up, complications, and progression. METHODS: The initial clinical examination was noted and completed by the examination under general anesthesia and the surgical or nonsurgical treatment proposed. RESULTS: Fifty-six eyes of 52 children were included: 19 anterior forms, four posterior, 25 mixed, and eight eyes already operated on in other centers. Fifty eyes had surgical treatment. At the end of follow-up, 13 eyes had a vision equal to or greater than 20/200 (23%) including five that were better than 20/100 (9%). Average follow-up was 32.5 months. CONCLUSIONS: Persistence of the fetal vascular system is a group of complex ocular malformations requiring an early diagnosis and well-adapted management.