A Burdorf1, B Järvholm, S Siesling. 1. Department of Public Health, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands. a.burdorf@erasmusmc.nl
Abstract
OBJECTIVE: In several countries the incidence of peritoneal mesotheliomas among women closely mirrors the pattern among men. The aim was to investigate the role of asbestos exposure in the aetiology of peritoneal mesotheliomas in women and men. METHODS: All cases of peritoneal mesothelioma were selected from the Swedish and Netherlands Cancer Registers for the period 1989-2003. For both countries incidence rates were calculated and stratified by sex. A linear regression analysis was used to analyse the existence of a trend over time. RESULTS: Among men the incidence rate of peritoneal mesothelioma in the Netherlands (0.60 per 100 000 persons) was consistently higher than in Sweden with an average ratio of 1.8 (range 1.4-2.8). In both countries no trend over time was observed. During the 15-year period in the Netherlands the incidence rate among men was about 3.3-fold higher than among women. In Sweden the incidence rate among women was slightly higher than in men up to 1999, and thereafter about threefold higher among men. This sudden shift was statistically significant and seemed mainly caused by changes in classification of peritoneal tumours. CONCLUSION: The absence of a time trend in the incidence rate of peritoneal mesothelioma in the Netherlands and Sweden in the past 15 years may point to a more limited role of occupational exposure to asbestos in the aetiology of peritoneal mesothelioma than for pleural mesothelioma, especially among women. The observed drop around 2000 in annual incidence of peritoneal mesothelioma among Swedish women indicates the presence in the past of a substantial misclassification with other tumours in the peritoneum.
OBJECTIVE: In several countries the incidence of peritoneal mesotheliomas among women closely mirrors the pattern among men. The aim was to investigate the role of asbestos exposure in the aetiology of peritoneal mesotheliomas in women and men. METHODS: All cases of peritoneal mesothelioma were selected from the Swedish and Netherlands Cancer Registers for the period 1989-2003. For both countries incidence rates were calculated and stratified by sex. A linear regression analysis was used to analyse the existence of a trend over time. RESULTS: Among men the incidence rate of peritoneal mesothelioma in the Netherlands (0.60 per 100 000 persons) was consistently higher than in Sweden with an average ratio of 1.8 (range 1.4-2.8). In both countries no trend over time was observed. During the 15-year period in the Netherlands the incidence rate among men was about 3.3-fold higher than among women. In Sweden the incidence rate among women was slightly higher than in men up to 1999, and thereafter about threefold higher among men. This sudden shift was statistically significant and seemed mainly caused by changes in classification of peritoneal tumours. CONCLUSION: The absence of a time trend in the incidence rate of peritoneal mesothelioma in the Netherlands and Sweden in the past 15 years may point to a more limited role of occupational exposure to asbestos in the aetiology of peritoneal mesothelioma than for pleural mesothelioma, especially among women. The observed drop around 2000 in annual incidence of peritoneal mesothelioma among Swedish women indicates the presence in the past of a substantial misclassification with other tumours in the peritoneum.
Authors: Victor L Roggli; Anupama Sharma; Kelly J Butnor; Thomas Sporn; Robin T Vollmer Journal: Ultrastruct Pathol Date: 2002 Mar-Apr Impact factor: 1.094
Authors: Fabio Montanaro; Freddie Bray; Valerio Gennaro; Enzo Merler; Jerzy E Tyczynski; Donald Maxwell Parkin; Marija Strnad; Marie Jechov'a; Hans H Storm; Tiiu Aareleid; Timo Hakulinen; Michel Velten; Hacina Lef'evre; Arlette Danzon; Antoine Buemi; Jean-Pierre Daur'es; François Ménégoz; Nicole Raverdy; Martine Sauvage; Hartwig Ziegler; Harry Comber; Eugenio Paci; Marina Vercelli; Vincenzo De Lisi; Rosario Tumino; Roberto Zanetti; Franco Berrino; Giorgio Stanta; Frøydis Langmark; Jadwiga Rachtan; Ryszard Mezyk; Jerzy Blaszczyk; Plesko Ivan; Maja Primic-Zakelj; Alvaro Cañada Martínez; Isabel Izarzugaza; Joan Borràs; Carmen Martínez Garcia; Isabel Garau; Navarro Carmen Sánchez; Ardanaz Aicua; Lotti Barlow; Joachim Torhorst; Christine Bouchardy; Fabio Levi; Thomas Fisch; Nicole Probst; Otto Visser; Mike Quinn; Anna Gavin; David Brewster; Marica Mikov Journal: Cancer Causes Control Date: 2003-10 Impact factor: 2.506
Authors: Melpo Christofidou-Solomidou; Ralph A Pietrofesa; Kyewon Park; Steven M Albelda; Kinta M Serve; Deborah E Keil; Jean C Pfau Journal: Toxicol Appl Pharmacol Date: 2019-04-23 Impact factor: 4.219
Authors: Dario Consonni; Cristina Calvi; Sara De Matteis; Dario Mirabelli; Maria Teresa Landi; Neil E Caporaso; Susan Peters; Roel Vermeulen; Hans Kromhout; Barbara Dallari; Angela Cecilia Pesatori; Luciano Riboldi; Carolina Mensi Journal: Occup Environ Med Date: 2019-07-08 Impact factor: 4.402
Authors: Rosa Talerico; Carmine Cardillo; Francesco De Vito; Francesca Schinzari; Manuel Soldato; Maria Cristina Giustiniani; Elena Verrecchia; Raffaele Manna Journal: Front Immunol Date: 2020-05-13 Impact factor: 7.561