Literature DB >> 17566911

Harzianums A and B produced by a fungal strain, Hypocrea sp. F000527, and their cytotoxicity against tumor cell lines.

H-Z Jin1, J-H Lee, W-D Zhang, H-B Lee, Y-S Hong, Y-H Kim, J-J Lee.   

Abstract

A new compound, harzianum B (1), was isolated from the culture broth of a fungal strain, Hypocrea sp. F000527, together with a known trichothecene, harzianum A (2). Its structure was determined by spectroscopic analyses including HRFAB-MS and various (1)H NMR and (13)C NMR spectral data. Harzianum B (1) was characterised as (E,Z,E)-2', 4', 6'-octatriendioic acid esterified on the 4beta-hydroxyl group of trichodermol. Harzianums A (2) and B (1) showed cytotoxicity against several human cancer cell lines.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17566911     DOI: 10.1080/10286020500531977

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  8 in total

1.  Identification of loci and functional characterization of trichothecene biosynthesis genes in filamentous fungi of the genus Trichoderma.

Authors:  R E Cardoza; M G Malmierca; M R Hermosa; N J Alexander; S P McCormick; R H Proctor; A M Tijerino; A Rumbero; E Monte; S Gutiérrez
Journal:  Appl Environ Microbiol       Date:  2011-06-03       Impact factor: 4.792

2.  Effects of Trichothecene Production on the Plant Defense Response and Fungal Physiology: Overexpression of the Trichoderma arundinaceum tri4 Gene in T. harzianum.

Authors:  R E Cardoza; S P McCormick; M G Malmierca; E R Olivera; N J Alexander; E Monte; S Gutiérrez
Journal:  Appl Environ Microbiol       Date:  2015-07-06       Impact factor: 4.792

3.  Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities.

Authors:  Sloan Ayers; Brandie M Ehrmann; Audrey F Adcock; David J Kroll; Esperanza J Carcache de Blanco; Qi Shen; Steven M Swanson; Joseph O Falkinham; Mansukh C Wani; Sheila M Mitchell; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Pept Sci       Date:  2012-06-29       Impact factor: 1.905

4.  Involvement of Trichoderma trichothecenes in the biocontrol activity and induction of plant defense-related genes.

Authors:  M G Malmierca; R E Cardoza; N J Alexander; S P McCormick; R Hermosa; E Monte; S Gutiérrez
Journal:  Appl Environ Microbiol       Date:  2012-05-04       Impact factor: 4.792

5.  A new species of Trichoderma hypoxylon harbours abundant secondary metabolites.

Authors:  Jingzu Sun; Yunfei Pei; Erwei Li; Wei Li; Kevin D Hyde; Wen-Bing Yin; Xingzhong Liu
Journal:  Sci Rep       Date:  2016-11-21       Impact factor: 4.379

6.  Herbicidal efficacy of harzianums produced by the biofertilizer fungus, Trichoderma brevicompactum.

Authors:  Miaomiao Yin; Opemipo Esther Fasoyin; Chen Wang; Qun Yue; Yunyun Zhang; Baoqing Dun; Yuquan Xu; Liwen Zhang
Journal:  AMB Express       Date:  2020-07-01       Impact factor: 3.298

7.  Antiproliferative and Antimicrobial Activities of Secondary Metabolites and Phylogenetic Study of Endophytic Trichoderma Species From Vinca Plants.

Authors:  Sahar Leylaie; Doustmorad Zafari
Journal:  Front Microbiol       Date:  2018-07-11       Impact factor: 5.640

8.  Characterisation of two unique sesquiterpenoids from Trichoderma hypoxylon.

Authors:  Jinyu Zhang; Wen-Bing Yin
Journal:  Mycology       Date:  2021-08-12
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.