Literature DB >> 1756597

Examination of the role of oxygen free radicals in bronchial asthma in childhood.

Z Novák1, I Németh, K Gyurkovits, S I Varga, B Matkovics.   

Abstract

The antioxidant enzyme activities, the lipid peroxidation level, the parameters of glutathione metabolism, and the proportion of haemoglobin oxidation products were determined during the symptom-free period of childhood bronchial asthma. A decreased catalase activity and a significantly reduced glutathione instability were demonstrated as compared to the controls. The results indicate that antioxidant protection of the haemoglobin molecule in asthmatic children is considerably decreased.

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Year:  1991        PMID: 1756597     DOI: 10.1016/0009-8981(91)90375-m

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  4 in total

Review 1.  Redox control of asthma: molecular mechanisms and therapeutic opportunities.

Authors:  Suzy A A Comhair; Serpil C Erzurum
Journal:  Antioxid Redox Signal       Date:  2010-01       Impact factor: 8.401

Review 2.  Nitric oxide metabolism in asthma pathophysiology.

Authors:  Sudakshina Ghosh; Serpil C Erzurum
Journal:  Biochim Biophys Acta       Date:  2011-06-21

3.  Lipid peroxidation in bronchial asthma.

Authors:  Anita Sharma; Satish Bansal; R K Nagpal
Journal:  Indian J Pediatr       Date:  2003-09       Impact factor: 1.967

4.  Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease.

Authors:  Alexey V Polonikov; Vladimir P Ivanov; Alexey D Bogomazov; Maxim B Freidin; Thomas Illig; Maria A Solodilova
Journal:  Biomed Res Int       Date:  2014-05-05       Impact factor: 3.411

  4 in total

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