BACKGROUND AND OBJECTIVE: This study investigated the healing of femtosecond laser created wounds in an animal model. STUDY DESIGN: We have assessed the healing of critical size wounds in mice calvaria using three different wounding techniques: carbide bur, diamond end-cutting bur, and ultrafast femtosecond laser, and in the presence or absence of bone morphogenetic protein-7 (BMP). Wound closure was examined using microcomputerized tomography at 3, 6, 9, and 12 weeks. RESULTS: Results have shown partial closure at up to 12 weeks with all techniques that did not involve the use of BMP, with the least closure noted in the laser groups as suggested by two-dimensional radiographic analysis. Bone volume measurements appeared slightly lower for the laser than for the mechanical groups, however statistically significant differences were seen only at week 6. No significant differences in closure were noted for the different methods in the BMP treated groups. CONCLUSIONS: Femtosecond laser cutting demonstrated an unsurpassed precision when compared to mechanical instruments. The addition of BMP led to very rapid healing with complete closure seen as early as 3 weeks and overcomes any potential healing delays that may arise from laser tissue cutting. (c) 2007 Wiley-Liss, Inc.
BACKGROUND AND OBJECTIVE: This study investigated the healing of femtosecond laser created wounds in an animal model. STUDY DESIGN: We have assessed the healing of critical size wounds in mice calvaria using three different wounding techniques: carbide bur, diamond end-cutting bur, and ultrafast femtosecond laser, and in the presence or absence of bone morphogenetic protein-7 (BMP). Wound closure was examined using microcomputerized tomography at 3, 6, 9, and 12 weeks. RESULTS: Results have shown partial closure at up to 12 weeks with all techniques that did not involve the use of BMP, with the least closure noted in the laser groups as suggested by two-dimensional radiographic analysis. Bone volume measurements appeared slightly lower for the laser than for the mechanical groups, however statistically significant differences were seen only at week 6. No significant differences in closure were noted for the different methods in the BMP treated groups. CONCLUSIONS: Femtosecond laser cutting demonstrated an unsurpassed precision when compared to mechanical instruments. The addition of BMP led to very rapid healing with complete closure seen as early as 3 weeks and overcomes any potential healing delays that may arise from laser tissue cutting. (c) 2007 Wiley-Liss, Inc.
Authors: Ma Cruz Lorenzo Luengo; M Portillo; J M Sánchez; M Peix; P Moreno; A García; J Montero; A Albaladejo Journal: Lasers Med Sci Date: 2012-07-04 Impact factor: 3.161
Authors: María Portillo Muñoz; María Cruz Lorenzo Luengo; José Miguel Sánchez Llorente; Manuel Peix Sánchez; Alberto Albaladejo; Ana García; Pablo Moreno Pedraz Journal: Lasers Med Sci Date: 2010-10-27 Impact factor: 3.161
Authors: Luke J Mortensen; Clemens Alt; Raphaël Turcotte; Marissa Masek; Tzu-Ming Liu; Daniel C Côté; Chris Xu; Giuseppe Intini; Charles P Lin Journal: Biomed Opt Express Date: 2014-12-05 Impact factor: 3.732
Authors: María Vicente Prieto; Ana Luisa Caseiro Gomes; Javier Montero Martín; Alfonso Alvarado Lorenzo; Vicente Seoane Mato; Alberto Albaladejo Martínez Journal: J Lasers Med Sci Date: 2016-10-27
Authors: Christina Plötz; Florian Schelle; Christoph Bourauel; Matthias Frentzen; Jörg Meister Journal: Lasers Med Sci Date: 2014-01-24 Impact factor: 3.161
Authors: Stephen J Baskey; Marco Andreana; Eric Lanteigne; Andrew Ridsdale; Albert Stolow; Mark E Schweitzer Journal: IEEE J Transl Eng Health Med Date: 2018-12-25 Impact factor: 3.316
Authors: David D Lo; Mark A Mackanos; Michael T Chung; Jeong S Hyun; Daniel T Montoro; Monica Grova; Chunjun Liu; Jenny Wang; Daniel Palanker; Andrew J Connolly; Michael T Longaker; Christopher H Contag; Derrick C Wan Journal: Lasers Surg Med Date: 2012-11-26 Impact factor: 4.025