OBJECT: In this study the authors compare the clinical outcomes after particle embolization of hemangioblastomas in the cerebellum and spinal cord. They also review the literature of similar cases. METHODS: Seven patients with hemangioblastomas in the spinal cord (four patients) and cerebellum (three patients) underwent preoperative embolization at the authors' center. Magnetic resonance imaging and selective angiography studies as well as histological diagnoses were available in all patients. Embosphere particles (trisacryl gelatin micro-spheres) were used in all cases. The smallest particle diameter ranged from 100 to 300 microm at the beginning of embolization in all patients. The outcome of embolization was favorable in patients with spinal cord hemangioblastomas, but it was unfavorable for those with cerebellar hemangioblastomas; acute tumor bleeding and death occurred in all of the latter cases. The outcomes following embolization are very different for these two locations possibly because of the different capillary sizes. CONCLUSIONS: The authors no longer use particle embolization to treat cerebellar hemangioblastomas.
OBJECT: In this study the authors compare the clinical outcomes after particle embolization of hemangioblastomas in the cerebellum and spinal cord. They also review the literature of similar cases. METHODS: Seven patients with hemangioblastomas in the spinal cord (four patients) and cerebellum (three patients) underwent preoperative embolization at the authors' center. Magnetic resonance imaging and selective angiography studies as well as histological diagnoses were available in all patients. Embosphere particles (trisacryl gelatin micro-spheres) were used in all cases. The smallest particle diameter ranged from 100 to 300 microm at the beginning of embolization in all patients. The outcome of embolization was favorable in patients with spinal cord hemangioblastomas, but it was unfavorable for those with cerebellar hemangioblastomas; acute tumor bleeding and death occurred in all of the latter cases. The outcomes following embolization are very different for these two locations possibly because of the different capillary sizes. CONCLUSIONS: The authors no longer use particle embolization to treat cerebellar hemangioblastomas.
Authors: Javier Ros de San Pedro; Fernando Alarcón Rodríguez; Belén Ferri Níguez; Juan F Martínez-Lage Sánchez; Antonio López López-Guerrero; Matías Felipe Murcia; Antonio M Ruíz-Espejo Vilar Journal: Neurosurg Rev Date: 2010-01 Impact factor: 3.042
Authors: Ali Harati; Jarno Satopää; Lydia Mahler; Romain Billon-Grand; Ahmed Elsharkawy; Mika Niemelä; Juha Hernesniemi Journal: Surg Neurol Int Date: 2012-01-21