| Literature DB >> 1756388 |
E A van der Zee1, G I de Jong, A D Strosberg, P G Luiten.
Abstract
The present study describes the colocalization of muscarinic acetylcholine receptors (mAChRs) and the calcium-binding protein parvalbumin (PARV) in nonpyramidal neurons of the rat dorsal hippocampus by means of dual-label immunocytochemistry. Fifty-two percent of all muscarinic cholinoceptive nonpyramidal neurons contain parvalbumin. Conversely, the vast majority (88.4%) of all PARVergic neurons possess mAChRs. The PARVergic neurons embedded within the CA1 pyramidal cell layer are nearly all (98.9%) immunopositive for mAChRs. These results indicate that the cholinergic septohippocampal projection represents a major afferent system upon the inhibitory PARVergic neurons.Entities:
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Year: 1991 PMID： 1756388 DOI： 10.1016/0361-9230(91)90048-o
Source DB: PubMed Journal: Brain Res Bull ISSN： 0361-9230 Impact factor: 4.077